Clinical Application of Nasal Filters: An Observational Study on the Usability of Nasal Filters in Managing Seasonal Allergic Rhinitis  Peter Kenney,

Slides:



Advertisements
Similar presentations
Nasal filters for the treatment of allergic rhinitis: A randomized, double-blind, placebo- controlled crossover clinical trial  Peter Kenney, BA, BSc,
Advertisements

Effect of 2-year placebo-controlled immunotherapy on airway symptoms and medication in patients with birch pollen allergy  Monica B. Arvidsson, MD, Olle.
Specificity and reproducibility of nasal biomarkers in patients with allergic rhinitis after allergen challenge chamber exposure  Philipp Badorrek, MD,
Advances in Diagnosing Peanut Allergy
Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses  Stephen R. Durham,
Oral Phenylephrine HCl for Nasal Congestion in Seasonal Allergic Rhinitis: A Randomized, Open-label, Placebo-controlled Study  Eli O. Meltzer, MD, Paul.
Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses  Stephen R. Durham,
Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5– grass pollen tablet for seasonal allergic rhinitis  Alain Didier, MD,
Findings from an Online Survey Assessing the Burden and Management of Seasonal Allergic Rhinoconjunctivitis in US Patients  Eli O. Meltzer, MD, Judith.
Vitamin D Insufficiency and Asthma in a US Nationwide Study
Auvi-Q Versus EpiPen: Preferences of Adults, Caregivers, and Children
Luciana Kase Tanno, MD, PhD, Moises A
Chronic Rhinosinusitis
Chronic rhinosinusitis: Potential new use for topical sulfasalazine
Complementary and Alternative Medicine in Allergy-Immunology: More Information is Needed  Leonard Bielory, MD  The Journal of Allergy and Clinical Immunology:
Efficacy of subcutaneous and sublingual immunotherapy with grass allergens for seasonal allergic rhinitis: A meta-analysis–based comparison  Danilo Di.
Dennis K. Ledford, MD, Sally Wenzel, MD 
Reducing the burden of allergy and asthma in schoolchildren: Air cleaning solutions and microbial diversity—the dark side of the moon?  João Cavaleiro.
Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis  Paul H. Ratner,
Is 9 more than 2 also in allergic airway inflammation?
Desensitization to Chemotherapeutic Agents
Clinical Application of Nasal Filters: An Observational Study on the Usability of Nasal Filters in Managing Seasonal Allergic Rhinitis  Peter Kenney,
Preventive effect of nasal filters on allergic rhinitis: A randomized, double-blind, placebo- controlled crossover park study  Peter Kenney, BSc, Ole Hilberg,
Bruce M. Prenner, MD, Bobby Q. Lanier, MD, David I
Intramuscular Versus Intravenous Immunoglobulin Replacement Therapy and Measurement of Immunoglobulin Levels During Immunoglobulin Replacement Therapy 
A Predictive Model for the Diagnosis of Allergic Drug Reactions According to the Medical History  Beatriz Hierro Santurino, MD, PhD, Javier Mateos Conde,
An Infant with Atopic Dermatitis and Itching After Ingestion of Milk
Robert S. Zeiger, MD, PhD, Michael Schatz, MD, MS, Anand A
Safety of Fluticasone Propionate Prescribed for Asthma During Pregnancy: A UK Population-Based Cohort Study  Rachel A. Charlton, PhD, Julia M. Snowball,
Nasal filters for the treatment of allergic rhinitis: A randomized, double-blind, placebo- controlled crossover clinical trial  Peter Kenney, BA, BSc,
Validation of the Pregnancy Asthma Control Test
Advances in Diagnosing Peanut Allergy
Self-Medication in Persistent Rhinitis: Overuse of Decongestants in Half of the Patients  Els Mehuys, MPharm, PhD, Philippe Gevaert, MD, PhD, Guy Brusselle,
Nonadherence to Asthma Treatment: Getting Unstuck
Reducing the burden of allergy and asthma in schoolchildren: Air cleaning solutions and microbial diversity—the dark side of the moon?  João Cavaleiro.
Successful treatment of idiopathic angioedema with ecallantide
Reply The Journal of Allergy and Clinical Immunology: In Practice
Aimee L. Speck, MD, Michael Hess, MSI, Alan P. Baptist, MD, MPH 
Laura Cordova-Rivera, BPhty(Hons), Peter G. Gibson, MBBS, Paul A
Management of Difficult-to-Treat Atopic Dermatitis
Repeated Episodes of Anaphylaxis with Normal Serum Tryptase but Elevated Levels of Urinary Prostaglandin D2  Phillip Lieberman, MD  The Journal of Allergy.
Penicillin Skin Testing Is a Safe and Effective Tool for Evaluating Penicillin Allergy in the Pediatric Population  Stephanie J. Fox, MD, Miguel A. Park,
Phillip Lieberman, MD, Michael Tankersley, MD 
Effects of Mometasone, Fluticasone, and Montelukast on Bone Mineral Density in Adults with Asthma  Jorge Maspero, MD, Vibeke Backer, DMSci, MD, Ruji Yao,
Atopic dermatitis: A practice parameter update 2012
Phillip Lieberman, MD, David Golden, MD 
Russell S. Traister, MD, PhD, Merritt L
Anaphylactic Reaction to White-Faced Hornet Sting and Elevated Baseline (Asymptomatic) Serum Tryptase  Phillip Lieberman, MD, Lawrence B. Schwartz, MD,
Association Between Asthma and Depression: A National Cohort Study
Linda S. Cox, MD, Cheryl Hankin, PhD, Richard Lockey, MD 
Neetu Talreja, MD, Richard F. Lockey, MD 
Sinonasal Papillomas and Natural Killer–Cell Deficiency
A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity  Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,
Sharon Seth, MD, David A. Khan, MD 
Cephalosporin Side Chain Cross-reactivity
Evaluation of Allergen Immunotherapy
Robert S. Zeiger, MD, PhD, Michael Schatz, MD, MS, Anand A
News & Notes Journal of Allergy and Clinical Immunology
Two ideas to improve mite allergen avoidance
Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment
Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis  Sriram Vaidyanathan, MBBS, Peter Williamson,
Is intralymphatic immunotherapy ready for clinical use in patients with grass pollen allergy?  Marianne Witten, MD, PhD, Hans-Jørgen Malling, MD, Lars.
Reply The Journal of Allergy and Clinical Immunology: In Practice
Long-term clinical efficacy in grass pollen–induced rhinoconjunctivitis after treatment with SQ-standardized grass allergy immunotherapy tablet  Stephen.
Piotr Kuna, MD, Jadwiga Kaczmarek, MD, Maciej Kupczyk, MD 
Nasal inflammatory mediators and specific IgE production after nasal challenge with grass pollen in local allergic rhinitis  Carmen Rondón, MD, PhD, Javier.
Clinical Management of Atopic Dermatitis: Practical Highlights and Updates from the Atopic Dermatitis Practice Parameter 2012  Peter A. Lio, MD, Margaret.
Pedro Giavina-Bianchi, MD, PhD, Shih-Wen Huang, MD 
The effects of an H3 receptor antagonist (PF ) with fexofenadine on reducing allergic rhinitis symptoms  Jeffrey R. Stokes, MD, Francisco A. Romero,
Natural history of cow’s milk allergy
Presentation transcript:

Clinical Application of Nasal Filters: An Observational Study on the Usability of Nasal Filters in Managing Seasonal Allergic Rhinitis  Peter Kenney, BSc, Ole Hilberg, MD, DMSci, Torben Sigsgaard, MD, PhD  The Journal of Allergy and Clinical Immunology: In Practice  Volume 4, Issue 3, Pages 445-452.e4 (May 2016) DOI: 10.1016/j.jaip.2016.01.003 Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 1 Study flow. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, 445-452.e4DOI: (10.1016/j.jaip.2016.01.003) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 2 Satisfaction shown as proportion + 95-CI. Of the 834 filter users in week 1, 796 used some form of medication; see Table E1 in this article's Online Repository at www.jaci-inpractice.org for details. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, 445-452.e4DOI: (10.1016/j.jaip.2016.01.003) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 3 Correlation between satisfaction with use and screening TNSSs. Too few participants had TNSS 0-3. Of the 834 filter users in week 1, 796 used some form of medication; see Table E1 in this article's Online Repository at www.jaci-inpractice.org for details. The Y-axis depicts percentages. See the text for Spearman's ρ and P values. TNSS, Total nasal symptom score. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, 445-452.e4DOI: (10.1016/j.jaip.2016.01.003) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 4 Correlation between satisfaction with use and asthma severity. Of the 834 filter users in week 1, 796 used some form of medication; see Table E1 in this article's Online Repository at www.jaci-inpractice.org for details. The Y-axis depicts percentages. Asthma severity was only rated at screening. See the text for Spearman's ρ and P values. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, 445-452.e4DOI: (10.1016/j.jaip.2016.01.003) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 5 Correlation between satisfaction with use in week 1 and satisfaction with use in week 2 for continued users (n = 634). The X-axis represents ratings in week 1. The Y-axis depicts percentages. See the text for Spearman's ρ and P values. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, 445-452.e4DOI: (10.1016/j.jaip.2016.01.003) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E1 A, The nasal filters. From left to right: a small, a medium, and a large nasal filter. B, A method of inserting the nasal filters (courtesy of Kenney et alE1). The Journal of Allergy and Clinical Immunology: In Practice 2016 4, 445-452.e4DOI: (10.1016/j.jaip.2016.01.003) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E2 Grass pollen counts from Copenhagen counted 15 meters above ground in 2014. The pollen calendar depicts mean daily pollen counts in the period 1985-2009. The study ran from May 31 until June 16. The graph is made available courtesy of The Danish Meteorological Institute (www.dmi.dk) and Asthma-Allergy Denmark. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, 445-452.e4DOI: (10.1016/j.jaip.2016.01.003) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E3 Correlation between satisfaction with use and overall allergy severity. Allergy severity was only reported at screening. The Y-axis depicts percentages. See the text for Spearman's ρ and P values. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, 445-452.e4DOI: (10.1016/j.jaip.2016.01.003) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions