VITAMINE-B 17: AN ALTERNATIVE TREATMENT OF CANCER Authors: Tanwar Rohit*, Kumar Naresh, Sanduja Mohit, Virmani Tarun & Gupta Jyoti School of Pharmaceutical Sciences, MVN University, Palwal ( Haryana)

ABSTRACT Vitamin B17, also called Amygdalin or laetrile, is a glycoside nutrient linked with cancer prevention in alternative medicine practices — and there are reliable claims that it’s actually cured cancer. Vitamin B17 is derived from natural food sources and most abundant in seeds of plants of the prunasin family, such as apricots and apples. Laetrile, the extract form of vitamin B17, is most well-known for potentially helping prevent cancer development through the production of hydrogen cyanide. This beneficial compound is released into the body’s tissues and targets and destroys mutated cells. Although more formal research is still needed to prove vitamin B17’s effectiveness, many alternative medicine practitioners use vitamin B17 to increase immunity. Cyanide is thought to be the main anti-cancer component of vitamin B17 but is not fully proven in clinical settings as of today.

INTRODUCTION Amygdalin was first discovered in 1830 in bitter almonds. Ernst. T. Krebs, Jr. (1912 - 1996) was a chemist who first promoted the amygdalin as a cancer drug in early 1950. From amygdalina made semi synthetic distillate calling it vitamin B17 or Laetrile. "in 1971, laetrile was banned. Dr. Richardson called on investigative journalist G. Edward Griffin to publicize the merits of laetrile or B17 derived from apricot seeds. Griffin discovered that the Sloane-Kettering Institute's laetrile trials leading to the FDA ban were bogus. Sloane-Kettering spokesperson Dr. Ralph Moss refused to lie about laetrile and left Sloane-Kettering in disgust. He slipped Griffin unpublicized papers scientifically proving laetrile actually worked. This led to Griffin's book A World Without Cancer, where you can read much more about the amygdalin cancer curing story.

CHEMISTRY OF VITAMIN B17 Chemical Names: Amygdalin; (R)-Amygdalin; 29883-15-6; D-Amygdalin; (R)-Laenitrile;    Molecular Formula: C20H27NO11 Molecular Weight:457.432 g/mol

MOA Laetrile, commonly known as Vitamin B17 or Amygdaline, contains two units of sugar, one of benzaldehyde and one of cyanide, all tightly locked with in it. Everyone knows that Cyanide ion can be highly toxic and even fatal if taken in sufficient quantity. However, as it is in locked state is completely inert and absolutely has no effect on living tissue. There is only one suabstance that can unlock this molecule and release the cyanide. That substance is an enzyme called beta- glycosidase, which we shall call the unlocking enzyme.

Some facts Laetrile is more effective in the control of cancer than any substance I have ever tested".   Doctor Kanematsu Sugiura, Sloan-Kettering Cancer Institute Of people who choose amygdalin therapy as their first choice cancer treatment about 85% will defeat their cancer."   G Edward Griffin "Incidentally, the gorilla in its natural habitat eats about 100 to 125 milligrams of Vitamin B17 a day, too. Like the population of Hunzaland, these gorillas are free of cancer Vitamin B-17 is one of the main sources of food in cultures such as the Eskimos, the Hunzas, the Abkhazians and many more. Did you know that within these tribes there has never been a reported case of cancer?"    Maybe the medical profession doesn’t like it because they are making too much money. Dr.Sugiura The FDA says B17 is Anti-Cancer

Helps To Protect Against Cancer . Helps To Protect Against Cancer Boost immunity Vitamin-B17 Benefits Reduce Pain Lower High Blood Pressure

. Berry Strawberry Source of Vitamin-B17 Apricot Apple Bitter Almond

Conclusion From many decades this natural drug kept hidden from the knowledge of people as its anti-cancer property.intead of taking costly synthetic drug,we can treat it with natural drug which have no side effect as compared to synthetic drug which are very toxic to our body. Reference Liegner KB, Beck EM, Rosenberg A (1981) Laetrile-induced agranulocytosis. JAMA 246(24):2841–2842 (Dec 18) Donaldson MS (2004) Nutrition and cancer: a review of the evidence for an anti-cancer diet. Nutr J 3(1):19 (Oct 20) Krebs ET Jr (1970) The nitrilosides (vitamin B17)—their nature, occurrence and metabolic significance antineoplastic vitamin B17. J Appl Nutr 22:75–86 Young VR, Newberne PM (1981) Vitamins and cancer prevention: issues and dilemmas. Cancer 47(Suppl 5):1226–1240 (Mar 1) Moertel CG, Fleming TR, Rubin J, Kvols LK, Sarna G, Koch R, Currie VE, Young CW, Jones SE, Davignon JP (1982) A clinical trial of amygdalin (laetrile) in the treatment of human cancer. N Engl J Med 306(4):201–206