Reversible posterior leukoencephalopathy syndrome and silent cerebral infarcts are associated with severe acute chest syndrome in children with sickle.

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Reversible posterior leukoencephalopathy syndrome and silent cerebral infarcts are associated with severe acute chest syndrome in children with sickle cell disease by Jessica N. Henderson, Michael J. Noetzel, Robert C. McKinstry, Desiree A. White, Melissa Armstrong, and Michael R. DeBaun Blood Volume 101(2): January 15, 2003 ©2003 by American Society of Hematology

MRI findings for case 1.Multifocal areas of fluid-attenuated inversion recovery (FLAIR) T2- weighted signal abnormality in the subcortical white matter and overlying gray matter of the frontal, parietal, and occipital lobes (bottom). Jessica N. Henderson et al. Blood 2003;101: ©2003 by American Society of Hematology

MRI findings for case 2.Multifocal areas of signal hyperintensity predominantly limited to the cortex of the posterior parietal and occipital lobes on FLAIR T2-weighted images, including punctate areas of abnormality in the deep, periventricular white matte... Jessica N. Henderson et al. Blood 2003;101: ©2003 by American Society of Hematology

MRI findings for case 3.(A) Extensive areas of FLAIR T2-weighted signal hyperintensity in the subcortical white matter and overlying gray matter of the posterior, frontal, and occipital lobes. Jessica N. Henderson et al. Blood 2003;101: ©2003 by American Society of Hematology

Characterization of T2-weighted hyperintensities on MRI of the brain distinguishing cerebral infarct from reversible posterior leukoencephalopathy syndrome (RPLS).DWI indicates diffusion weighted image; DC, diffusion coefficient. Jessica N. Henderson et al. Blood 2003;101: ©2003 by American Society of Hematology