2004-2005 Principles of Medical Science Pharmacology Review 28 April 2017 6:51 PM
Amikacin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
Aminoglycosides Antibiotics Bactericidal protein synthesis inhibitors 30S ribosome Freeze initiation
Amoxicillin Penicillin antibiotic Cell wall synthesis inhibitor Antiulcer Amino penicillin Inhibits peptidoglycan cross-linking
Ampicillin Penicillin antibiotic Cell wall synthesis inhibitor Amino penicillin Inhibits peptidoglycan cross-linking
Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation
New b lactam antibiotic Aztreonam New b lactam antibiotic Monobactam
Bacitracin Antibiotic Cell wall synthesis inhibitor Topical, not a b lactam, Inhibits dephosphorylation of bactoprenol
Benzathine penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Inhibits peptidoglycan cross-linking Repository preparation
Carbenicillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
Cephalosporin antibiotic Cell wall synthesis inhibitor Cefaclor Cephalosporin antibiotic Cell wall synthesis inhibitor 2nd generation Oral
Cephalosporin antibiotic Cell wall synthesis inhibitor Cefadroxil Cephalosporin antibiotic Cell wall synthesis inhibitor 1st generation Oral
Cefepime Cephalosporin antibiotic Cell wall synthesis inhibitor 4th generation CSF penetration
Cefotaxime Cephalosporin antibiotic Cell wall synthesis inhibitor 3rd generation CSF penetration
Cephalosporin antibiotic Cell wall synthesis inhibitor Cefoxitin Cephalosporin antibiotic Cell wall synthesis inhibitor 2nd generation
Cephalosporin antibiotic Cell wall synthesis inhibitor Ceftazidime Cephalosporin antibiotic Cell wall synthesis inhibitor 3rd generation
Ceftriaxone Cephalosporin antibiotic Cell wall synthesis inhibitor 3rd generation CSF penetration
Cefuroxime Cephalosporin antibiotic Cell wall synthesis inhibitor 2nd generation CSF penetration
Cephalosporin antibiotic Cell wall synthesis inhibitor Cephalexin Cephalosporin antibiotic Cell wall synthesis inhibitor 1st generation Oral
Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan Cephalosporins Antibiotics b lactam Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan
Cephalosporin antibiotic Cell wall synthesis inhibitor Cephalothin Cephalosporin antibiotic Cell wall synthesis inhibitor 1st generation Oral
Chloramphenicol Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits peptide bond formation
Ciprofloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase
50S ribosome Inhibits translocation Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation
b-lactamase inhibitor Combined with antibacterials Clavulanic acid b-lactamase inhibitor Combined with antibacterials
Clindamycin Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Anaerobic infections
Penicillin antibiotic Cell wall synthesis inhibitor Cloxacillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking
Cycloserine Antibiotic Cell wall synthesis inhibitor Secondary TB drug Inhibits formation of Park nucleotide
Dapsone Sulfone antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Leprosy
Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation
Fluorinated Quinolones ciprofloxacin, norfloxacin Antibiotics DNA replication inhibitors Inhibit bacterial DNA gyrase
Gentamicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
Imipenem/Cilastatin New b lactam antibiotic Cilastatin inhibits a kidney dipeptidase that inactivates imipenem
Oxazolidinone antibiotic Protein synthesis inhibitor Linezolid Oxazolidinone antibiotic Protein synthesis inhibitor 50S ribosomal subunit
Macrolides erythromycin, azithromycin, clarithromycin Antibiotics Bacteriostatic protein synthesis inhibitors 50S ribosome
Methicillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking
Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA
Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
Penicillin antibiotic Cell wall synthesis inhibitor Nafcillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking
Neomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation Topical
Netilmicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
Norfloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase
Oxacillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking
Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
Para-aminosalicylic acid Antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Secondary TB drug
Penicillins b lactam antibiotics Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan
Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Acid labile Inhibits peptidoglycan cross-linking
Penicillin antibiotic Cell wall synthesis inhibitor Penicillin V Penicillin antibiotic Cell wall synthesis inhibitor More acid resistant than Penicillin G Inhibits peptidoglycan cross-linking
Piperacillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
Polymyxin B Antibiotic Disrupts gram negative cell membrane Binds phosphatidylethanolamine Bactericidal
Adjunct in penicillin therapy Probenecid Uricosuric Adjunct in penicillin therapy
Procaine Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Repository preparation Inhibits peptidoglycan cross-linking
Quinopristin/Dalfopristin Streptogramin antibiotic Protein synthesis inhibitor 50S ribosomal subunit
Rifampin Antibiotic Nucleic acid synthesis inhibitor Inhibits DNA dependent RNA polymerase Major drug for TB
Inhibits dihydropteroate synthetase Topical Silver sulfadiazine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical
Antibiotic Bacteriostatic protein synthesis inhibitor Spectinomycin Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome
Streptomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
Inhibits dihydropteroate synthetase Topical Sulfacetamide Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical
Dihydropteroate synthetase inhibitor Sulfadoxine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Dihydropteroate synthetase inhibitor
Inhibits dihydropteroate synthetase Sulfamethoxazole Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase
Sulfisoxazole Sulfonamide antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase
Sulfonamides Antibiotics Nucleic acid and protein synthesis inhibitors Inhibit dihydropteroate synthetase
Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment
Ticarcillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
Tobramycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
Trimethoprim Antibiotic Protein and nucleic acid synthesis inhibitor Folic acid antagonist Inhibits bacterial dihydrofolate reductase
Antibiotic Inhibits cell wall synthesis Vancomycin Antibiotic Inhibits cell wall synthesis Not a b lactam