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2004-2005 Fluids & Electolytes Pharmacology Review 9 June 2016 7:16 AM.

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Presentation on theme: "2004-2005 Fluids & Electolytes Pharmacology Review 9 June 2016 7:16 AM."— Presentation transcript:

1 2004-2005 Fluids & Electolytes Pharmacology Review 9 June 2016 7:16 AM

2 Acebutolol Sympatholytic  1 adrenergic antagonist Class II antiarrhythmic Antihypertensive Antianginal Bronchoconstrictor

3 Acetazolamide Diuretic Carbonic anhydrase inhibitor

4 Alendronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption

5 Amikacin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

6 Amiloride Potassium sparing diuretic Sodium channel inhibitor Antihypertensive

7 Aminoglycosides Antibiotics Bactericidal protein synthesis inhibitors 30S ribosome Freeze initiation

8 Amlodipine Antihypertensive Calcium channel blocker

9 Amoxicillin Penicillin antibiotic Cell wall synthesis inhibitor Antiulcer Amino penicillin Inhibits peptidoglycan cross-linking

10 Ampicillin Penicillin antibiotic Cell wall synthesis inhibitor Amino penicillin Inhibits peptidoglycan cross-linking

11 Atenolol Sympatholytic  1 adrenergic antagonist Antihypertensive Antiarrhythmic Antianginal Bronchoconstrictor

12 Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

13 Aztreonam New  lactam antibiotic Monobactam

14 Bacitracin Antibiotic Cell wall synthesis inhibitor Topical, not a  lactam, Inhibits dephosphorylation of bactoprenol

15 Benazopril Antihypertensive Converting enzyme inhibitor

16 Benzathine penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Inhibits peptidoglycan cross-linking Repository preparation

17 Betaxolol Sympatholytic  1 adrenergic antagonist Antihypertensive Glaucoma medication Bronchoconstrictor

18 Bretylium Sympatholytic Class III antiarrhythmic K + channel blocker

19 Bumetanide Loop diuretic Na + -K + -2Cl - transporter inhibitor

20 Captopril Antihypertensive Converting enzyme inhibitor Heart failure treatment Angioedema producer

21 Carbenicillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

22 Carteolol Sympatholytic  adrenergic antagonist Antihypertensive Bronchoconstrictor

23 Cefaclor Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation Oral

24 Cefadroxil Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

25 Cefepime Cephalosporin antibiotic Cell wall synthesis inhibitor 4 th generation CSF penetration

26 Cefotaxime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration

27 Cefoxitin Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation

28 Ceftazidime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation

29 Ceftriaxone Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration

30 Cefuroxime Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation CSF penetration

31 Cephalexin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

32 Cephalosporins Antibiotics  lactam Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan

33 Cephalothin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

34 Chloramphenicol Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits peptide bond formation

35 Chlorthalidone Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive

36 Chlorothiazide Thiazide diuretic Na-Cl symporter inhibitor

37 Ciprofloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase

38 Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation

39 Clavulanic acid  -lactamase inhibitor Combined with antibacterials

40 Clindamycin Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Anaerobic infections

41 Clonidine Sympatholytic  2 adrenergic agonist Antihypertensive

42 Cloxacillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking

43 Cycloserine Antibiotic Cell wall synthesis inhibitor Secondary TB drug Inhibits formation of Park nucleotide

44 Dapsone Sulfone antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Leprosy

45 Desmopressin acetate Synthetic analogue of arginine vasopressin Used in treatment of bleeding disorders

46 Diazoxide Vasodilator Antihypertensive

47 Diltiazem Class IV antiarrhythmic Antihypertensive Ca 2+ channel blocker

48 Doxazosin Sympatholytic  1 adrenergic antagonist Antihypertensive

49 Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

50 Enalapril Antihypertensive Converting enzyme inhibitor Angioedema producer

51 Eplerenone Aldosterone receptor antagonist

52 Eprosartan Antihypertensive Angiotensin receptor blocker (ARB)

53 Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

54 Esmolol Sympatholytic  1 adrenergic antagonist Class II Antiarrhythmic Antihypertensive Bronchoconstrictor

55 Ethacrynic acid Loop diuretic Na-K-2Cl symporter inhibitor

56 Etidronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption

57 Felodipine Antihypertensive Calcium channel blocker

58 Fluorinated Quinolones ciprofloxacin, norfloxacin Antibiotics DNA replication inhibitors Inhibit bacterial DNA gyrase

59 Fosinopril Antihypertensive Converting enzyme inhibitor

60 Furosemide Loop diuretic Na-K-2Cl symporter inhibitor Antihypertensive

61 Gentamicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

62 Guanabenz Sympatholytic Antihypertensive

63 Guanadrel Sympatholytic Antihypertensive

64 Guanethidine Sympatholytic Antihypertensive

65 Guanfacine Sympatholytic  2 adrenergic agonist Antihypertensive

66 Hydralazine Vasodilator Antihypertensive

67 Hydrochlorothiazide Thiazide diuretic Na-Cl symporter inhibitor Antihypertensive

68 Imipenem/Cilastatin New  lactam antibiotic Cilastatin inhibits a kidney dipeptidase that inactivates imipenem

69 Indapamide Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive

70 Irbesartan Antihypertensive Angiotensin receptor blocker (ARB)

71 Isradipine Antihypertensive Calcium channel blocker

72 Labetalol Sympatholytic  and  adrenergic antagonist Antihypertensive

73 Linezolid Oxazolidinone antibiotic Protein synthesis inhibitor 50S ribosomal subunit

74 Losartan Antihypertensive Angiotensin receptor blocker (ARB)

75 Lypressin Antidiuretic hormone analogue

76 Macrolides erythromycin, azithromycin, clarithromycin Antibiotics Bacteriostatic protein synthesis inhibitors 50S ribosome

77 Mannitol Osmotic diuretic

78 Methenamine Urinary tract antiseptic Decomposes to formaldehyde in acidic environment

79 Methicillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

80 Methydopa Sympatholytic  2 adrenergic agonist Antihypertensive

81 Metolazone Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive

82 Metoprolol Sympatholytic  1 adrenergic antagonist Antihypertensive Heart failure medication Bronchoconstrictor

83 Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA

84 Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

85 Minoxidil Vasodilator Antihypertensive

86 Nadolol Sympatholytic  adrenergic antagonist Antihypertensive

87 Nafcillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking

88 Nalidixic acid Urinary tract antiseptic Quinolone Inhibits bacterial DNA gyrase

89 Neomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation Topical

90 Netilmicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

91 Nicardipine Antihypertensive Calcium channel blocker

92 Nifedipine Antihypertensive Antianginal Calcium channel blocker

93 Nisoldipine Antihypertensive Calcium channel blocker

94 Nitrendipine Antihypertensive Calcium channel blocker

95 Nitrofurantoin Urinary tract antiseptic Reduction leads to intermediates that damage DNA

96 Nitroglycerine Venodilator Antianginal

97 Nitroprusside Vasodilator Antihypertensive

98 Norfloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase

99 Oxacillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

100 Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

101 Pamidronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption

102 Para-aminosalicylic acid Antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Secondary TB drug

103 Penbutolol Sympatholytic  adrenergic antagonist Antihypertensive Bronchoconstrictor

104 Penicillins  lactam antibiotics Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan

105 Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Acid labile Inhibits peptidoglycan cross-linking

106 Penicillin V Penicillin antibiotic Cell wall synthesis inhibitor More acid resistant than Penicillin G Inhibits peptidoglycan cross-linking

107 Phenoxybenzamine Sympatholytic  adrenergic antagonist Antihypertensive

108 Phentolamine Sympatholytic  adrenergic antagonist Antihypertensive

109 Pindolol Sympatholytic  adrenergic antagonist Antihypertensive Bronchoconstrictor

110 Piperacillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

111 Polymyxin B Antibiotic Disrupts gram negative cell membrane Binds phosphatidylethanolamine Bactericidal

112 Prazosin Sympatholytic  1 adrenergic antagonist Antihypertensive

113 Probenecid Uricosuric Adjunct in penicillin therapy

114 Procaine Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Repository preparation Inhibits peptidoglycan cross-linking

115 Propranolol Sympatholytic  adrenergic antagonist Class II antiarrhythmic Antihypertensive Bronchoconstrictor

116 Quinapril Antihypertensive Converting enzyme inhibitor

117 Quinethazone Thiazide-like diuretic Na-Cl symporter inhibitor

118 Quinopristin/Dalfopristin Streptogramin antibiotic Protein synthesis inhibitor 50S ribosomal subunit

119 Ramipril Antihypertensive Converting enzyme inhibitor

120 Reserpine Sympatholytic Antihypertensive

121 Rifampin Antibiotic Nucleic acid synthesis inhibitor Inhibits DNA dependent RNA polymerase Major drug for TB

122 Silver sulfadiazine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

123 Spectinomycin Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome

124 Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatment

125 Streptomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

126 Sulfacetamide Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

127 Sulfadoxine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Dihydropteroate synthetase inhibitor

128 Sulfamethoxazole Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

129 Sulfisoxazole Sulfonamide antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

130 Sulfonamides Antibiotics Nucleic acid and protein synthesis inhibitors Inhibit dihydropteroate synthetase

131 Telmisartan Antihypertensive Angiotensin receptor blocker (ARB)

132 Terazosin Sympatholytic  1 adrenergic antagonist Antihypertensive Treatment for benign prostatic hypertrophy

133 Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment

134 Ticarcillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

135 Timolol Sympatholytic  adrenergic antagonist Antihypertensive Glaucoma treatment Anti-anginal Bronchoconstrictor

136 Tobramycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

137 Tosemide Loop diuretic Na-K-2Cl symporter inhibitor

138 Triamterene Potassium sparing diuretic Sodium channel inhibitor Antihypertensive

139 Trimethaphan Sympatholytic Anticholinergic Nicotinic antagonist Antihypertensive

140 Trimethoprim Antibiotic Protein and nucleic acid synthesis inhibitor Inhibits bacterial dihydrofolate reductase

141 Valsartan Antihypertensive Angiotensin receptor blocker (ARB)

142 Vancomycin Antibiotic Inhibits cell wall synthesis Not a  lactam

143 Arginine vasopressin (Antidiuretic hormone; ADH) Hypothalamic (posterior pituitary) hormone Antidiuretic Vasoconstrictor

144 Verapamil Class IV antiarrhythmic Antihypertensive L-type Ca 2+ channel blocker Antianginal


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