lab 9 G6PD Daheeya AlEnazi

Principle Glucose 6 p + NADP+ G6PDH gluconate 6P+NADPH+ H+ NADPH will florescence under UV light if there is deficiency of enzyme NO florescence will appear. G6PDH= glucose 6 phosphate dehydrogenase

Clinical significant G6PD deficiency is an inherited condition in which the body doesn't have enough of the enzyme glucose-6-phosphate dehydrogenase, which helps RBCs function normally. This deficiency can cause hemolytic anemia, usually after exposure to certain medications, foods, or infections. Most people with G6PD deficiency don't have any symptoms, while others develop symptoms of anemia only after RBCs have been destroyed, a condition called hemolysis. In these cases, the symptoms disappear once the cause, or trigger, is removed. In rare cases, G6PD deficiency leads to chronic anemia

Causes of G6PD Deficiency: G6PD deficiency is passed along in genes from one or both parents to a child. The gene responsible for this deficiency is on the X chromosome Sample: will be whole blood.

Result under UV light Normal Deficient