A Cost Effective Centralized Single parameter Patient Monitoring System Abstract Lack of Medical monitoring equipment's in rural areas of underdeveloped regions results in an inefficiency in health care facilities,in this abstract we propose to build an open source centralized cost effective patient monitoring system keeping in mind mobility, cost, power and real-time access, Using this system we can deliver basic PMS parameters and real time excess to rural hospitals. Introduction  Patient Monitoring System (PMS): PMS is a very critical system, it is used for monitoring physiological signals including Electrocardiograph (ECG), Respiration, Invasive and Non-Invasive Blood Pressure, Oxygen Saturation in Human Blood (SpO2), Body Temperature and other Gases etc. In PMS, the multiple sensor and electrodes is used for receiving physiological signals like as ECG Electrodes, SpO2 Finger Sensor, Blood Pressure Cuff and Temperature Probe to measure the physiological signals.  Parameters in Patient Monitoring System: ECG 3/5/10 :Electrocardiography is a transthoracic interpretation of the electrical activity of the heart over a period of time, as detected by electrodes attached to the surface of the skin and recorded by a device external to the body. Respiration:l respiratory rates and changes in respiratory rate are a broad indicator of major physiological instability, and in many cases, respiratory rate is one of the earliest indicators of this instability,The nasal / mouth airflow sensor is a device used to measure the breathing rate in a patient in need of respiratory help or person. This device consists of a flexible thread which fits behind the ears, and a set of two prongs which are placed in the nostrils. Breathing is measured by these prongs. Blood Pressure (BP):Blood pressure is the pressure of the blood in the arteries as it is pumped around the body by the heart. When your heart beats, it contracts and pushes blood through the arteries to the rest of your body. This force creates pressure on the arteries. Blood pressure is recorded as two numbers—the systolic pressure (as the heart beats) over the diastolic pressure (as the heart relaxes between beats). Dual Temperature :Body temperature depends upon the place in the body at which the measurement is made, and the time of day and level of activity of the person. Different parts of the body have different temperatures. SpO2 :Pulse oximetry a non-invasive method of indicating the arterial oxygen saturation of functional haemoglobin. Oxygen saturation is defined as the measurement of the amount of oxygen dissolved in blood, based on the detection of Haemoglobin and Deoxyhaemoglobin Two different light wavelengths are used to measure the actual difference in the absorption spectra of HbO2 and Hb and hence SpO2  Current Challenges : Convectional PMS aren't built keeping in mind the power effectiveness and rural environment,although in recent years many open source health monitoring designs have emerged but they still does not address the both cost and power issues.  Main Objective : To develop a cost effective easy to use basic PMS system allowing patients to be monitored in real-time.  Motivation : To improve healthcare facilities of rural areas in underdeveloped regions by providing basic medical monitoring devices. System Software Design Conceptual Design  Proposed System Architecture and Hardware: Key design considerations are : Mobility Power efficiency Cost Real-time and remote access System Hardware Design Block Diagram of Proposed System Block Diagram of Hardware Architecture Proposed Software Design  Many existing systems support the networking of bedside monitors to a central monitor via a vendor-specific communication interface here we are trying to integrate the data of many patients to a single window but are also providing the option to access it my a mobile device.  The hardware reduces the cost of Individual Monitor and discreet components for individual patients by integrating them into a single board connected to raspberry Pi although the Key challenge here is also to achieve good signal strength by signal conditioning and high sampling rate.  We also propose to incorporate emergency battery to board and raspberry Pi which is very crucial in rural areas where power supply is irregular.  Communication Raspberry Pi and GR-Sakura board : Custom GUI application for linux/Android( based on Python) by using Qt- py,Numpy, matplot and wiring-python libraries. Real-time patient monitoring data. Instructions to biosensors. Biosensors setting status. Connection establishment and maintenance messages Conclusion A new patient monitoring system is proposed :  The monitoring system brings the cost down by achieving integration of Sensors to a single analog board and microcontroller.  With Custom software we can receive, transmit, and display data to remote location.  Quality of patient care and increase the efficiency of medical staff.  The System can be further extended to do multiple task as patient monitoring as well as patient management system.  The Module can also be used for health monitoring during Natural calamity and disaster.