Health Care Connected: Next Generation Pharmacy February 13, 2016

2015= Hepatitis C $$$$ 2016 and Beyond: Strategies to control Specialty Drug cost and improve outcomes

3 Pharmacy impacts all health care costs Pharmacy represents 20% of health care costs … yet it can dramatically affect the other 80% of spend 1. AHIP Coverage, 2013; 2. Kaiser/HRET Survey of Employer Health Benefits, 2013; 3. IMS Health, National Sales Perspectives, Dec 2014; 4. IMS Institute for Healthcare Informatics. Avoidable Costs in U.S. Healthcare % Missed Opportunities are not taken as prescribed 2 50% of medications Fragmented Experience & Care leave doctor not understanding what they were told 1 50% of patients Increased Cost in specialty pharmacy costs over last 5 years 3 $54B increase Generics Brands Specialty

4 Clinical Solutions Standard ToolkitInnovation ‘Now’ Standard Formulary Suite Utilization Management Concurrent DUR Retrospective DUR Fraud Waste & Abuse Mgmt Adherence Monitoring & Intervention Care Gap Impact Medication Therapy Management Therapeutic Interchange High-Risk Meds in Elderly Provider Profiling Transitional Care Readmission Prevention Tech-Enabled Diabetes Care Mgmt Outcomes-Driven PhRMA Contracting Multidimensional Specialty Care Management Prospective Pipeline Review, Forecasting & P&T Deliberation SECURE Compound Mgmt Program & Industry’s 1 st & Only Credentialed Compound Network Patterns of Care Provider Profiling Generic Inflation Solution Suite

5 CONTINUED MANAGEMENT OF THE MOST EXPENSIVE MEDICATIONS Today Implementation of new drug polices Expansion of genetic testing and lab value requirements Expansion of preferred products across benefits Expansion of redirection to lower-cost sites of services Expansion of utilization management programs 28 drug policies - over 100 drugs Prior authorization with medical necessity Preferred products Redirect to lower-cost sites Clinical claim edits Administrative guide protocols Required specialty pharmacy sourcing Tomorrow Medical utilization management

6 Expansion of medical necessity NOTIFICATION / PRIOR AUTHORIZATION MEDICAL NECESSITY Coverage is based on approved or proven uses of the medication Coverage is approved if treatment is deemed medically necessary Drug Diagnosis Dose Duration Genetic Testing Dose Titration Evaluation of Response Treatment Guidelines Preferred Product Site of Service Expanded clinical and cost effectiveness review with medical necessity vs. traditional approach

Improving patient well being

8 Smart touch approach to patient care BETTER CARE THROUGH DATA AND ANALYTICS

9 BriovaLive™ INCREASED COMFORT AND ADHERENCE THROUGH VIDEO CONSULTATIONS

10 Our video consult capability provides education with a personalized touch Review medications & supplies Assemble device (if needed) Injection training Storing procedures *Catamaran/BriovaRx study 7% improvement in adherence after participating in a video consultation.* Side effects Drug interactions Questions Support & reassurance BriovaLive™

11 BriovaCommunity™ GREATER UNDERSTANDING THROUGH PERSONALIZED VIDEOS

12 BriovaCommunity™ Testimonials from peers with similar illnesses Tailored websites and videos to help members better understand their conditions and live healthier lives Information on conditions and treatments Tips on medication adherence and side-effect management Introduction to BriovaRx ® care team members Advice from expert physicians and clinicians Guidance on diet, meditation and other lifestyle topics 10% Better persistency and adherence for Harvoni patients using BriovaCommunity™ * *internal analysis

13 Assure Current Plan Design and Administration is addressing : -Priior Authorization -Step Therapy -Quantity Limits -Site of Service -Rebate transparency Leverage International Union PBM programs -Preferred pricing -Contract terms -Service Model Explore Regional Labor Alliances -Coalition pricing -Audit rights -Contract terms Specialty Drug Strategies for Fund Trustee Consideration