1. CELLS INVOLVED IN THE IMMUNE RESPONSE

3. A. HUMORAL LIQUID PART OF THE BLOOD

4. 1)PLASMA 5% OF BODY WEIGHT MAINLY WATER

6. 2) SERUM PROTEIN PART OF BLOOD, MORE VISCOUS THAN PLASMA

7. a)COMPLEMENT: PROTEINS WHICH LYSE ANTIBODY COATED CELLS

8. b)ANTIBODIES: GLYCOPROTEINS WHICH BIND TO ANTIGENS

11. B. CELLULAR

12. 1)PLATELETS: THROMBOCYTES CLOT THE BLOOD

14. 2) RED BLOOD CELLS – ERYTHROCYTES

16. RED BLOOD CELLS CARRY O2 USE IRON IN HEMOGLOBIN

17. 3) WHITE BLOOD CELLS - LEUKOCYTES

18. FUNCTIONS: 1. PHAGOCYTOSIS 2. PRODUCE ANTI- BODIES

19. 3. CLEAN BLOOD CLOTS 4. KILL CELLS ON CONTACT

20. A.GRANULOCYTES GRAINY CYTOPLASM INFLAMMATORY MEDIATORS

21. 1.NEUTROPHILS: 50 – 70% MOST ABUNDANT 100 BILLION PRODUCED/DAY

22. 1 ST AT SITE OF INJURY DIAPEDESIS – SQUEEZE THRU CAPILLARIES

24. 2. BASOPHILS.5 – 1% INCREASE IN BACTERIAL/ VIRAL INFECTIONS

25. INFLAMMATORY MEDIATORS – RELEASE HISTAMINE HEPARIN

27. 3. ESINOPHILS: 1 – 5% INCREASE IN WORMS, ALLERGIES

28. KILL ON CONTACT DIGEST EXTRACELLULAR PARASITES

30. 4. NATURAL KILLER CELLS

31. KILL CANCER CELLS FOREIGN GRAFTS VIRUS INFESTED CELLS

33. B. AGRANULOCYTES: LACK A GRAINY CYTOPLASM AND ARE NOT INFLAMMATORY INITIATORS

34. 1.MACROPHAGES 2. 2 – 6% 3. CALLED MONOCYTES IN CIRCULATION

35. 4. FOLLOW NEUTROPHILS TO SITE 5. ANTIGEN PRESENTING CELL

37. 2. DENDRITIC CELLS – ANTI- GEN PRESENTING CELL

38. COMMON AT MUCUS MEMBRANES

39. MAY ACTUALLY PRESENT HIV VIRUSES TO TH CELLS

41. 3. LYMPHOCYTES: MAKE UP 20 – 30 %

42. A. T – LYMPHO- CYTES

43. SPEND TIME IN THE THYMUS

44. DISCOVERED IN THE 1950 ’ S AND 1960 ’ S MANY TYPES

45. 1)T HELPER CELLS AKA – CD4 CELLS PRESENT ANTIGENS TO B CELLS

47. 2)CYTOTOXIC T CELLS – TCYTO AKA – CD8 CELLS

48. LYSE CELLS ON CONTACT – THIS DESTROYS VIRUS INFESTED CELLS

50. 3)T REGULATORY/ T SUPPRESSOR CELL – SLOW DOWN IMMUNE RESPONSE

51. PREVENT OVER- KILL

52. 4)T DELAYED TYPE HYPER- SENSITIVITY CELL

53. INVOLVED WITH DELAYED TYPE ALLERGIES – LIKE POISON IVY, METALS

54. B –LYMPHOCYTES OR B CELLS PRODUCE ANTI- BODIES

55. B CELLS THAT PRODUCE ANTIBODIES ARE KNOWN AS PLASMA CELLS

57. USUALLY REQUIRE ACTIVATION THROUGH THE T HELPER CELLS