1. ON YOUR OWN:  In your notebook, brainstorm EVERYTHING you already know about DNA  It’s okay if you think it’s wrong, write it down

2. WITH TABLE GROUP:  In your own notebook, add together all the things the other people thought of that you didn’t  Erase/fix anything the other people taught you that you may have thought incorrectly  Should have a BIG list now!

3. SHARE OUT:  EACH TABLE MUST SHARE 1 IDEA FROM THEIR GROUP- 1 each round  NO REPEATS!!!  THIS MEANS YOU NEED TO PAY ATTENTION  WE WILL KEEP GOING UNTIL WE CAN’T FIND ANY MORE

4. DRAW A LINE BELOW YOUR NOTES  WATCH THE VIDEO  DNA Structure DNA Structure  WRITE DOWN AS MANY DETAILS AS YOU CAN CATCH  WE WILL WATCH MULTIPLE TIMES SO IF YOU MISS IT THE FIRST TIME, TRY TO CATCH IT NEXT TIME  SHARE OUT  WATCH AGAIN

5. Highlight as we go along  Everything you already have in your notes that you see in my notes- highlight it!!!  In the end, we will see what you noticed about DNA.

6. VOCABULARY  Mono- one  Poly- many/multiple  De- to take away or get rid of

7. VOCABULARY  DNA: deoxyribonucleic acid  (de-oxy-ribo-nucleic)  Sugar- deoxyribose  RNA: ribonucleic acid  (ribo-nucleic)  Sugar- ribose

8. Phosphate group Nitrogenous base (adenine) Sugar Nucleotides have three parts –Sugar –Phosphate –Nitrogenous Base

9. Nitrogenous bases  Adenine (A)  Thymine (T)  Cytosine (C)  Guanine (G ) Copyright © 2009 Pearson Education, Inc. sugar phosphate

10. A/T T C/G G PHOSPHATES SUGARS A Adenine G Guanine T Thymine C Cytosine

11. Pyrimidines Guanine (G) Adenine (A) Cytosine (C)Thymine (T) Purines

12. Sugar-phosphate backbone DNA nucleotide Phosphate group Nitrogenous base Sugar DNA polynucleotide DNA nucleotide Sugar (deoxyribose) Thymine (T) Nitrogenous base (A, G, C, or T) Phosphate group

13. Nucleic acids  Two polynucleotide strands- DNA double helix –Hydrogen Bonds  base pairs Copyright © 2009 Pearson Education, Inc.

14. Twist

15. Hydrogen bond Base pair Partial chemical structureComputer model Ribbon model

16. The Central Dogma  A sequence forms a gene  Every cell- millions of base pairs and hundreds of genes –DNA –RNA –Proteins (Structures and Functions) Copyright © 2009 Pearson Education, Inc.

17. Let’s Review!!!  What were some things you saw in my notes that you already had in your notes?

18. LET’S MAKE SOME DNA! * SPECIAL LABELLING DIRECTIONS  Every group needs:  45- Phosphates (dark purple circle)  36- Deoxyribose (mint green pentagon)*  9- Ribose (pink pentagon)*  13- Adenine (red pentagon/hexagon)*  10- Thymine (yellow hexagon)*  10- Cytosine (green hexagon)*  10- Guanine (blue pentagon/hexagon)*  2- Uracil (light purple hexagon)*

19. LET’S BUILD IT: BUILD IT IN THE SAME ORDER AS ME, AND THEN FINISH THE SEQUENCE: Place it on your paper first, and I will double check you have done it correctly before you glue it down. TGCGTACATTGCGTACAT

20. LET’S BUILD IT:  WHAT DOES THE OTHER SIDE LOOK LIKE? BUILD IT!!!

21. ADD TO YOUR LIST  WHAT DO YOU NOTICE ABOUT YOUR DNA STRANDS?  WRITE DOWN MORE DETAILS ON YOUR LIST

22. DO NOW What are the three parts of a nucleotide?