1. Chapter 17 – Blood $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Can’t Squeeze Blood from a Turnip F oreign B lood I nvestigators Are You My Type? You’re a Pint Low Thicker than H 2 O FINAL ROUND

2. Can’t Squeeze Blood from a Turnip: $100 Question There are ~280 million Hb molecules in one RBC. A single Hb molecule carries ___ molecule(s) of O 2, which means that a single RBC carries about ___ O 2 molecules. a. 1 / 280 million b. 8 / 2 billion c. 2 / 1 million d. 4 / 1 billion BACK TO GAME ANSWER

3. Can’t Squeeze Blood from a Turnip: $100 Answer There are ~280 million Hb molecules in one RBC. A single Hb molecule carries ___ molecule(s) of O 2, which means that a single RBC carries about ___ O 2 molecules. a. 1 / 280 million b. 8 / 2 billion c. 2 / 1 million d. 4 / 1 billion BACK TO GAME

4. Can’t Squeeze Blood from a Turnip: $200 Question All of the following except ___ leads to a decrease in HCT. a. Dehydration b. Hemorrhage c. Problems with RBC formation d. Anemia BACK TO GAME ANSWER

5. Can’t Squeeze Blood from a Turnip: $200 Answer All of the following except ___ leads to a decrease in HCT. a. Dehydration b. Hemorrhage c. Problems with RBC formation d. Anemia BACK TO GAME

6. Can’t Squeeze Blood from a Turnip: $300 Question Why is it important that the iron – oxygen interaction in oxyhemoglobin is weak? a. So that an irreversible bond forms between oxygen and the hemoglobin is weak b. So that oxygen may dissociate into tissues c. Because RBCs consume some of the oxygen they carry d. Because carbon dioxide has a higher affinity for the iron molecule BACK TO GAME ANSWER

7. Can’t Squeeze Blood from a Turnip: $300 Answer Why is it important that the iron – oxygen interaction in oxyhemoglobin is weak? a. So that an irreversible bond forms between oxygen and the hemoglobin is weak b. So that oxygen may dissociate into tissues c. Because RBCs consume some of the oxygen they carry d. Because carbon dioxide has a higher affinity for the iron molecule BACK TO GAME

8. Can’t Squeeze Blood from a Turnip: $400 Question What accounts for males’ HCT (~46) being higher than females’ HCT (~42)? a. Males are larger than females. b. Females’ RBCs are smaller than males’ RBCs. c. Androgens stimulate RBC production. d. Estrogens breakdown RBCs at a faster rate than they are produced. BACK TO GAME ANSWER

9. Can’t Squeeze Blood from a Turnip: $400 Answer What accounts for males’ HCT (~46) being higher than females’ HCT (~42)? a. Males are larger than females. b. Females’ RBCs are smaller than males’ RBCs. c. Androgens stimulate RBC production. d. Estrogens breakdown RBCs at a faster rate than they are produced. BACK TO GAME

10. Can’t Squeeze Blood from a Turnip: $500 Question Under normal conditions, what is the fate of the globular proteins of a recycled hemoglobin molecule? a. They are filtered by the kidneys and eliminated in urine. b. They are disassembled into their component amino acids. c. They are stripped of their heme unit and converted into biliverdin. d. They are converted to bilirubin and excreted in bile. BACK TO GAME ANSWER

11. Can’t Squeeze Blood from a Turnip: $500 Answer Under normal conditions, what is the fate of the globular proteins of a recycled hemoglobin molecule? a. They are filtered by the kidneys and eliminated in urine. b. They are disassembled into their component amino acids. c. They are stripped of their heme unit and converted into biliverdin. d. They are converted to bilirubin and excreted in bile. BACK TO GAME

12. F oreign B lood I nvestigators: $100 Question All of the following except ___ are characteristics of all types of WBCs. a. They can leave capillaries by diapedesis b. They are capable of amoeboid movement c. They are phagocytic d. They are attracted to specific chemical stimuli BACK TO GAME ANSWER

13. F oreign B lood I nvestigators: $100 Answer All of the following except ___ are characteristics of all types of WBCs. a. They can leave capillaries by diapedesis b. They are capable of amoeboid movement c. They are phagocytic d. They are attracted to specific chemical stimuli BACK TO GAME

14. F oreign B lood I nvestigators: $200 Question What is the nature of and purpose of surface antigens on RBCs? a. Glycoproteins in the cytoplasm / Substances that your body recognizes as foreign b. Receptor proteins / They aid the entry of oxygen to RBCs c. Peripheral proteins / They trigger an immune response d. Integral membrane glycoproteins or glycolipids / Substances your immune system recognizes as “normal” BACK TO GAME ANSWER

15. F oreign B lood I nvestigators: $200 Answer What is the nature of and purpose of surface antigens on RBCs? a. Glycoproteins in the cytoplasm / Substances that your body recognizes as foreign b. Receptor proteins / They aid the entry of oxygen to RBCs c. Peripheral proteins / They trigger an immune response d. Integral membrane glycoproteins or glycolipids / Substances your immune system recognizes as “normal” BACK TO GAME

16. F oreign B lood I nvestigators: $300 Question Which type of WBC is found in greatest numbers in an infected cut? a. Monocytes b. Neutrophils c. B lymphocytes d. Eosinophils BACK TO GAME ANSWER

17. F oreign B lood I nvestigators: $300 Answer Which type of WBC is found in greatest numbers in an infected cut? a. Monocytes b. Neutrophils c. B lymphocytes d. Eosinophils BACK TO GAME

18. F oreign B lood I nvestigators: $400 Question Monocytes transform into ____ in tissues, where they ____. a. Basophils / Exacerbate inflammation b. Plasma cells / Synthesize and release antibodies c. Macrophages / Are phagocytic and release chemicals that attract neutrophils d. Natural Killer cells / Detect and destroy abnormal tissue cells BACK TO GAME ANSWER

19. F oreign B lood I nvestigators: $400 Answer Monocytes transform into ____ in tissues, where they ____. a. Basophils / Exacerbate inflammation b. Plasma cells / Synthesize and release antibodies c. Macrophages / Are phagocytic and release chemicals that attract neutrophils d. Natural Killer cells / Detect and destroy abnormal tissue cells BACK TO GAME

20. F oreign B lood I nvestigators: $500 Question Sam has an infestation of large parasitic worms. Which of the following will happen? a. Eosinophils will release cytotoxic enzymes from their granules. b. Lymphocytes will engulf the worms by phagocytosis. c. Basophils will release histamine. d. All types of WBCs will be damaged by the parasites, causing leukopenia. BACK TO GAME ANSWER

21. F oreign B lood I nvestigators: $500 Answer Sam has an infestation of large parasitic worms. Which of the following will happen? a. Eosinophils will release cytotoxic enzymes from their granules. b. Lymphocytes will engulf the worms by phagocytosis. c. Basophils will release histamine. d. All types of WBCs will be damaged by the parasites, causing leukopenia. BACK TO GAME

22. Are You My Type?: $100 Question If Sarah has surface antigen A on her RBCs, what blood type does she have? What type of antibodies are in her plasma? a. O / Anti-A and anti-B b. B / Anti-A c. A / Anti-B d. AB / None BACK TO GAME ANSWER

23. Are You My Type?: $100 Answer If Sarah has surface antigen A on her RBCs, what blood type does she have? What type of antibodies are in her plasma? a. O / Anti-A and anti-B b. B / Anti-A c. A / Anti-B d. AB / None BACK TO GAME

24. Are You My Type?: $200 Question Christopher has blood type O. What type(s) can he receive from a donor? Why? a. O / He has anti-A and anti B antibodies in his plasma b. A, B, or O / He has no surface antigens on his RBCs c. A or O / He has anti-B surface antigens on his RBCs d. None of the above is correct. BACK TO GAME ANSWER

25. Are You My Type?: $200 Answer Christopher has blood type O. What type(s) can he receive from a donor? Why? a. O / He has anti-A and anti B antibodies in his plasma b. A, B, or O / He has no surface antigens on his RBCs c. A or O / He has anti-B surface antigens on his RBCs d. None of the above is correct. BACK TO GAME

26. Are You My Type?: $300 Question Why can’t a person with Type A blood safely receive blood from a person with Type B blood? a. Mixing blood types causes infections in the recipient. b. The anti-A antibodies in Type A’s plasma would react with Type B’s donated blood. c. Type B blood would agglutinate in the recipient’s blood vessels and plug small vessels to vital organs. d. All of the above are correct. BACK TO GAME ANSWER

27. Are You My Type?: $300 Answer Why can’t a person with Type A blood safely receive blood from a person with Type B blood? a. Mixing blood types causes infections in the recipient. b. The anti-A antibodies in Type A’s plasma would react with Type B’s donated blood. c. Type B blood would agglutinate in the recipient’s blood vessels and plug small vessels to vital organs. d. All of the above are correct. BACK TO GAME

28. Are You My Type?: $400 Question Why is it unlikely that the antibodies in a Type O donors plasma would cause a transfusion reaction in a Type A recipient? a. Surface antigens on RBCs are more important in determining compatibility. b. The plasma portion of donated blood is tiny when compared to the volume of plasma in the recipient’s body. c. Plasma is not transfused in blood donations. d. O blood doesn’t have any antibodies in it s plasma. BACK TO GAME ANSWER

29. Are You My Type?: $400 Answer Why is it unlikely that the antibodies in a Type O donors plasma would cause a transfusion reaction in a Type A recipient? a. Surface antigens on RBCs are more important in determining compatibility. b. The plasma portion of donated blood is tiny when compared to the volume of plasma in the recipient’s body. c. Plasma is not transfused in blood donations. d. O blood doesn’t have any antibodies in it s plasma. BACK TO GAME

30. Are You My Type?: $500 Question Why is cross-matching performed, though both donor and recipient are known to be the same blood type? a. It reveals the presence of potential cross-reactions with surface antigens other than A, B, and Rh. b. It ensures that neither donor nor recipient is anemic. c. It confirms the HIV status of the donor. d. It ensures that the donor does not have WBCs outside the normal range. BACK TO GAME ANSWER

31. Are You My Type?: $500 Answer Why is cross-matching performed, though both donor and recipient are known to be the same blood type? a. It reveals the presence of potential cross-reactions with surface antigens other than A, B, and Rh. b. It ensures that neither donor nor recipient is anemic. c. It confirms the HIV status of the donor. d. It ensures that the donor does not have WBCs outside the normal range. BACK TO GAME

32. You’re a Pint Low: $100 Question Which of the phases of hemostasis occurs first? a. Platelet phase b. Vascular phase c. Fibrinolysis phase d. Coagulation phase BACK TO GAME ANSWER

33. You’re a Pint Low: $100 Answer Which of the phases of hemostasis occurs first? a. Platelet phase b. Vascular phase c. Fibrinolysis phase d. Coagulation phase BACK TO GAME

34. You’re a Pint Low: $200 Question A deficiency of albumin in plasma contributes to ___. a. A decrease in the ability for blood to clot b. A decrease in the ability to fight infection c. A decrease in osmotic pressure and decrease in transport of fatty acids d. A decrease in transport of hormone binding proteins and steroid binding proteins BACK TO GAME ANSWER

35. You’re a Pint Low: $200 Answer A deficiency of albumin in plasma contributes to ___. a. A decrease in the ability for blood to clot b. A decrease in the ability to fight infection c. A decrease in osmotic pressure and decrease in transport of fatty acids d. A decrease in transport of hormone binding proteins and steroid binding proteins BACK TO GAME

36. You’re a Pint Low: $300 Question Which of the following is not true of platelets? a. They are packets of cytoplasm produced from megakaryocytes. b. They release chemicals important to clotting. c. Their formation is stimulated by thrombopoietin. d. There are about 3.5 million platelets in a microliter of blood. BACK TO GAME ANSWER

37. You’re a Pint Low: $300 Answer Which of the following is not true of platelets? a. They are packets of cytoplasm produced from megakaryocytes. b. They release chemicals important to clotting. c. Their formation is stimulated by thrombopoietin. d. There are about 3.5 million platelets in a microliter of blood. BACK TO GAME

38. You’re a Pint Low: $400 Question Tracey has been diagnosed with pernicious anemia. Which of the following conditions contributed to his illness? a. He has a vitamin B 12 deficiency. b. He has more than the normal percentage of RBCs. c. He has an iron deficiency. d. He is producing too much intrinsic factor. BACK TO GAME ANSWER

39. You’re a Pint Low: $400 Answer Tracey has been diagnosed with pernicious anemia. Which of the following conditions contributed to his illness? a. He has a vitamin B 12 deficiency. b. He has more than the normal percentage of RBCs. c. He has an iron deficiency. d. He is producing too much intrinsic factor. BACK TO GAME

40. You’re a Pint Low: $500 Question Which condition(s) stimulate the release of EPO? What is/are effects of EPO? a. The presence of deoxyhemoglobin in the blood / Decreases the rate of hemoglobin synthesis b. Blood flow to the kidneys declines / Stimulates increase in cell division rates of erythroblasts c. Moving to a high altitude / Speeds up maturation of RBCs d. B and C are correct. BACK TO GAME ANSWER

41. You’re a Pint Low: $500 Answer Which condition(s) stimulate the release of EPO? What is/are effects of EPO? a. The presence of deoxyhemoglobin in the blood / Decreases the rate of hemoglobin synthesis b. Blood flow to the kidneys declines / Stimulates increase in cell division rates of erythroblasts c. Moving to a high altitude / Speeds up maturation of RBCs d. B and C are correct. BACK TO GAME

42. Thicker than H 2 O: $100 Question In which organ are most plasma proteins synthesized? a. Spleen b. Bone marrow c. Kidneys d. Liver BACK TO GAME ANSWER

43. Thicker than H 2 O: $100 Answer In which organ are most plasma proteins synthesized? a. Spleen b. Bone marrow c. Kidneys d. Liver BACK TO GAME

44. Thicker than H 2 O: $200 Question All of the following except ____ is a major function of blood. a. Transport of dissolved gases, nutrients and hormones b. Stabilization of body temperature c. Provides storage for calcium ions d. Defense against toxins and pathogens BACK TO GAME ANSWER

45. Thicker than H 2 O: $200 Answer All of the following except ____ is a major function of blood. a. Transport of dissolved gases, nutrients and hormones b. Stabilization of body temperature c. Provides storage for calcium ions d. Defense against toxins and pathogens BACK TO GAME

46. Thicker than H 2 O: $300 Question Why is venipuncture a common technique for obtaining a blood sample? a. Blood pressure is relatively low in veins. b. Superficial veins are easy to locate. c. Venous walls are thinner than arterial walls. d. All of the above are correct. BACK TO GAME ANSWER

47. Thicker than H 2 O: $300 Answer Why is venipuncture a common technique for obtaining a blood sample? a. Blood pressure is relatively low in veins. b. Superficial veins are easy to locate. c. Venous walls are thinner than arterial walls. d. All of the above are correct. BACK TO GAME

48. Thicker than H 2 O: $400 Question What is the primary difference between plasma and interstitial fluid? a. Plasma contains significantly more protein. b. Interstitial fluid contains no respiratory gases. c. The concentration of ions is significantly less in plasma. d. Interstitial fluid contributes very little to the volume of ECF in the body. BACK TO GAME ANSWER

49. Thicker than H 2 O: $400 Answer What is the primary difference between plasma and interstitial fluid? a. Plasma contains significantly more protein. b. Interstitial fluid contains no respiratory gases. c. The concentration of ions is significantly less in plasma. d. Interstitial fluid contributes very little to the volume of ECF in the body. BACK TO GAME

50. Thicker than H 2 O: $500 Question Which characteristics of blood contribute to its high viscosity? a. Its temperature is slightly above body temperature? b. Interactions among proteins, formed elements, and water molecules in plasma c. Its alkalinity d. The percentage of body weight it comprises BACK TO GAME ANSWER

51. Thicker than H 2 O: $500 Answer Which characteristics of blood contribute to its high viscosity? a. Its temperature is slightly above body temperature? b. Interactions among proteins, formed elements, and water molecules in plasma c. Its alkalinity d. The percentage of body weight it comprises BACK TO GAME

52. FINAL ROUND Question What contributions from the Extrinsic and Intrinsic Pathways help form the enzyme complex necessary to begin the Common Pathway? a. Factors VIII and IX from the Extrinsic pathway / Factor VII from the Intrinsic pathway b. Factor III from the Extrinsic pathway / Factor XII from the Intrinsic pathway c. Factor VII from the Extrinsic Pathway / Factors VIII and IX from the Intrinsic d. None of the above is correct. BACK TO GAME ANSWER

53. FINAL ROUND Answer What contributions from the Extrinsic and Intrinsic Pathways help form the enzyme complex necessary to begin the Common Pathway? a. Factors VIII and IX from the Extrinsic pathway / Factor VII from the Intrinsic pathway b. Factor III from the Extrinsic pathway / Factor XII from the Intrinsic pathway c. Factor VII from the Extrinsic Pathway / Factors VIII and IX from the Intrinsic d. None of the above is correct. BACK TO GAME