1. DAFNE Consortium An italian supply chain collaboration story WWW.CONSORZIODAFNE.COM L. Bodini – Consortium DAFNE President GIRP: Brussels, 24 June 2013

2. DAFNE is a Consortium in the pharmaceutical chain, composed by da pharmaceutical companies and wholesalers, founded in 1992. DAFNE is a Consortium in the pharmaceutical chain, composed by da pharmaceutical companies and wholesalers, founded in 1992. Stakeholders actually involved represent more than 99% of the italian market. Stakeholders actually involved represent more than 99% of the italian market. Its a B2B community and the mission is to achieve a partnership inside the pharmaceutical chain to optimize distribution processes and the related administrative activities. Its a B2B community and the mission is to achieve a partnership inside the pharmaceutical chain to optimize distribution processes and the related administrative activities. Integration between partners its realized thruogh projects of IT connection based on standard procedure and role ( Internet or EDI ). Integration between partners its realized thruogh projects of IT connection based on standard procedure and role ( Internet or EDI ). During last years, DAFNE Consortium has promoted these activities also in the public health system. During last years, DAFNE Consortium has promoted these activities also in the public health system. DAFNE Consortium is a nonprofit entity DAFNE Consortium is a nonprofit entity The consortium

3. DAFNE Organisation chart Board of management 6 Pharma C.ny + 6 Distr. C.ny 1 Managing director Technical Commettee Logistic and Administrative Team Hospitals Team Partners annual meeting Activities areas Hospitals Orders trasmission Financials Electronic invoice, payments, reconc. Logistics Order transmission, order tracking, std Delivery Deliveries tracking

4. 68 Pharmaceutical companies 39 Distribution companies 70 Distribution companies Consortium stakeholders (al 2012 ) GXS – IT Partner IntesaSanpaolo Bank 40 Storage companies 110 Public hospitals

5. 5 40 Users partner DHL S.C.– Dimaf/Ceva – Chiapparoli – Fiege/Farmanova – Ferlito – Pieffe/UPS – Phardis – Monico –Profarco – Neologistica- Sidis – Ruoppolo – Jacopetti – Farmos - Cabassi&Giuriati – Profarma – Columbus – De Salute – Tonacci – Pharmidea – STM - Viprof – Welc.Pharma – Demas- Alloga – CPS – Felpharma – Sanifarma – Depofarma – Pluripharma – Fagit – CD Pharma - Salvia Farm. – Puleo – Gramma – Pasquali – Mazzoleni Benessere – Eurodifarm – Cesareo Farmacosm – J&J Medical AFM (BO) AllianceHealthcare Al-Pharma Confarma Cedifar C.E.F. Cofarmit. Comifar Coofarma Salento Corofar Co.Si.Far. Cotifa Difar DM Barone Farcopa Farla soc.coop. Farmaca Cannone Farmacentro S & L Farmadistribuzione Farmintesa Logistica Farvima FCR (RE) Felletti & Spadazzi Galenitalia Galeno Guacci Lemarfarma Nord Est Farma Ravenna Farmacie Re Roberto Riccobono Safar Sofarmamorra Unico Unione Farm.Liguri Unioneffe Unifarm Unifarma V.I.M. Abbott AbbVie ABC Farmaceutici Aboca Actavis Alcon Allergan Amgen Dompè Angelini Artsana Astellas Astra Zeneca Avantgarde Baxter Bayer B.Braun Beiersdorf Biofotura Boehringer Ingel. Bracco Bristol M.S Bruno farmaceutici Chiesi Co.Di.Fi Coloplast Convatec Cosmetique Act.e CSL Behring Daiichi Sankyo Eli Lilly EG-Crinos Euritalia FederFarmaco Ferring Fidia GlaxoS.K. (+Viiv) Grunenthal Guna Heinz Inneov Johnson&Johnson Lab. Boiron Lab. SVR Medtronic Mellin Merck S.D. Merck Serono Mylan 68 Pharma Companies Named Novartis Nutricia Pensa Pfizer Pierre Fabre Promefarm Ranbaxy Recordati. Reckitt B. Roche Ratiopharm Rottapharm Sandoz Sanofi-Aventis Schaer Sigma Tau Sixtus Skills in farm. Teva 39 Distrib. companies + 70 Distrib. Companies users

6. DAFNE : order to cash process Supplier Customer Bank OrderDeliveryInvoicingPayment Data alig.

7. DAFNE Pharma C.ny Distr. C.ny Logist. Prov.

8. DAFNE flow GxS Partner Ord Ship. doc Inv Ord GXS Inv.

9. 1. Invoices archive ( active) 2. Electronic invoice exchange ( supplier - customer ) 3. Electronic structured exchange of all documents through all involved parts Digital business benefits ( source: Politecnico di Milano – Laboratorio Fatturazione elettronica e dematerializzazione ) from 1 to 2 /cycle from 0,6 to 4 /cycle ( not structurated ) from 5,5 a 8,5 /cycle ( structuradet ) from 24 to 65 /cycle

10. Paym. & recon. InvoiceDelivery Order Net benefits for pharmaceutical chain ( source: Politecnico di Milano – Laboratorio Fatturazione elettronica e dematerializzazione ) Da 24 cycle Electronic exchange already in place in Italian pharmacetical chain

11. DAFNE : documents volume exchange

12. New projects Deliveries Tracking Shipments problems management POD Inbound booking Transport KPI Payment Accounting reconciliation Carriers Bank

13. Value creation by process optimization through a cooperation with all stakeholders of the pharma chain System approach Why ? System Chain Company More efficiency, more saving

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