1. Large neuroblastoma showing patchy necrosis and haemorrhage excised surgically from a female aged 16 months occur within the adrenal medulla

2. Relatively mild acute pancreatitis. The pancreas appears mildly congested and foci of calcification (arrows) are present within the gland

3. Severe acute haemorrhagic pancreatitis.

4. The main changes occurring in pancreatitis are: Protease digestion of pancreatic substance Elastase digestion of blood vessels with subsequent haemorrhage Lipases digesting fat in the pancreas and in the peritoneal cavity Accompanying inflammatory reaction

5. Acute pancreatitis. The pre-existing architecture has been essentially destroyed Haemorrhage and necrosis of acute pancreatitis, with some preserved pancreatic parenchyma on the left

6. Focal acute necrosis of perirenal fat in a patient who had severe acute pancreatitis. The patient was oliguric due to acute renal tubular necrosis of ischaemic type. See the calcium deposition (arrows) highlighting foci of enzymatic fat necrosis.

7. Severe chronic pancreatitis in a male alcoholic aged 45

8. Chronic pancreatitis with atrophy of the exocrine component and replacement by fibrous tissue.