Presentation on theme: "Adrenal Masses: MR Imaging Features with Pathologic Correlation"— Presentation transcript:
1 Adrenal Masses: MR Imaging Features with Pathologic Correlation By :Nour Eldin MohammedRef: Khaled M. Elsayes, et al , 2004, Radiographics
2 Normal AnatomyThe adrenal glands are two small, yellowish bodies located in the perirenal space, immediately anterosuperior to the upper pole of the kidneys.They are very vascular and receive blood supply from the superior, middle, and inferior suprarenal arteries
4 The adrenal gland is composed of an outer cortex and thinner inner medulla. The cortex is further subdivided into three zones: outer zona glomerulosa, middle zona fasciculata, and inner zona reticularis
5 Normal MRI AppearanceThe right adrenal gland is located posterior to the inferior vena cava and superior to the upper pole of the right kidney.The left adrenal gland is anteromedial to the upper pole of the kidney and posterior to the pancreasNormal adrenal glands range from 2 to 6 mm in thickness and from 2 to 4 cm in length
6 Fat-containing Adrenal Masses Fat-containing adrenal masses can be classified into two main types:those that contain intracellular fat (eg, adenoma)and those with macroscopic fat (eg, myelolipoma).
7 Adrenal Adenoma The most common adrenal lesions. Characterised by the presence of intracellular lipid.Chemical shift imaging is the most reliable technique for diagnosing adrenal adenoma with loss of signal intensity on out-of-phase images.Uniform enhancement with contrast enhanced images is typical of adenomas.Cystic changes, hemorrhage, or variation in vascularity lead to small, rounded foci of altered signal intensity.
9 MyelolipomaThe myelolipoma is an uncommon benign tumor composed of mature adipose tissue and hematopoietic tissue.Mostly discovered accidentally.The fatty component of this tumor is hyperintense on T1- weighted images.With loss of signal intensity of the fatty component on Fat-Suppressed Technique.
10 Axial T1 with Fat Suppressed Technique Axial T1 MRI
11 Cystic MassesThese include :Simple CystsPseudocystsLymphangioma
13 PseudocystsPseudocysts typically arise after an episode of adrenal hemorrhage and do not have an epithelial lining.Have a complicated appearance on MR images, manifesting with septations, blood products, or a soft- tissue component secondary to hemorrhage or hyalinized thrombus.Peripheral curvilinear calcification may be present.
15 LymphangiomaLow signal intensity at T1-weighted imaging and high signal intensity at T2-weighted
16 Hypervascular Lesions (Pheochromocytoma) It arises from the adrenal medulla.10% of pheochromocytomas are bilateral,10% are extraadrenal,10% occur in children, and 10% are malignantPheochromocytomas do not contain a substantial amount of cytoplasmic lipid, So they maintain their signal intensity on out-of-phase GRE chemical shift images.Most pheochromocytomas demonstrate high signal intensity on T2-weighted images (light bulb sign).
17 Axial T1 in Phase MRIAxial T1 out of Phase MRIContrast-enhanced Image
19 Adrenocortical Carcinoma a rare tumor.Age :Large sizeCan manifest as a hyperfunctioning mass causing Cushing syndrome or Conn syndrome.Other manifestations include an abdominal mass and abdominal pain.
20 Sagittal 3D contrast-enhanced MRI Coronal T2-weighted MRI
21 Adrenal Lymphoma More with non-Hodgkin lymphoma Bilateral involvement occurs in 50% of patients .Characterized by low signal intensity on T1 WI and heterogeneous high signal intensity on T2 WI , with minimal progressive enhancement after administration of contrast material.
23 MetastasesThe most common malignant lesions involving the adrenal gland.Found in up to 27% of patients with Carcinomas at autopsy.Common primary sites of tumors that metastasize to the adrenal glands include the lung, bowel, breast, and pancreas.Usually bilateral but may also be unilateral.
24 Contrast Enhanced T1 Image Of Metastatic Deposit From Renal Cell Carcinoma
26 NeuroblastomaThe 2nd most common pediatric abdominal mass (after Wilms tumor).Representing 5%–15% of all malignant tumors in children .Arises from the neural crest in the adrenal medulla or along the sympathetic chain.Usually demonstrates heterogeneous low signal intensity on T1-weighted images, high signal intensity on T2-weighted images , and enhancement after administration of contrast material.Calcification is present in 80%–90% of the lesions
28 Ganglioneuroblastoma Intermediate in malignancy between that of neuroblastoma and ganglioneuromaarise from the neural crest.Ganglioneuroblastoma are smaller and more well defined than neuroblastomaDemonstrates Intermediate signal intensity on T1 WI and heterogeneously high signal intensity on T2 WI, with heterogeneous enhancement after administration of contrast material.
29 T1-WI shows a heterogeneous mass with intermediate signal intensity