1.  Do Now: List five (5) things that you know about cancer  Take out homework from Friday to review!  Vocabulary: cancer, tumor, benign, malignant, metastasis, cell cycle gene, tumor suppressor, oncogene, proto-oncogene, contact inhibition  Scrap book due Wednesday 11/12  CHANGE IN HW SCHECULE BELOW!  Read “Not an Old Person’s Disease” case study part 1 ACTIVELY (underline, take notes in the margin) for Wednesday.  HW page 252 due Friday 11/14

2.  Describe what happens during each of the phases of mitosis.  Describe what happens during interphase.  The cell grows (G1), replicates its chromosomes (S), and makes final preparations for mitosis (G2).  What are chromosomes made of?  Chromosomes are made of DNA, packed together with proteins.  How is cytokinesis in plants similar to cytokinesis in animal cells? How is it different?  In both cases, the cytoplasm divides. The difference is that in plant cells a cell plate forms, while in animal cells there is no cell plate.

3.  Look over multiple choice questions.  Determine which questions you answered incorrectly.  Review correct answers and formulate any questions you have.

5.  Cancer is a term for diseases in which abnormal cells divide without control and can invade other tissues.  Cancer cells can spread to other parts of the body through the blood and lymph systems ( National Cancer institute )lymph  Cancer is not just one disease but many diseases. There are more than 100 different types of cancer.

6. Go to Section: Contact Inhibition: Cells normally stop multiplying when they come in contact with other cells. This is mediated by cell cycle genes. Cells with mutated cell cycle genes continue to multiply, even when other cells are in close contact. Think Pair Share Based on the definition for cancer, describe how these petri dishes would look if one of these cells became cancerous? Why?

7. Review the data presented in the graph on the worksheet and answer all questions. 1. How likely is it that you will develop colon cancer this year? 2. How likely is it that someone who is 60 years old will develop colon cancer? 3. How likely is it that someone who is 80 will develop colon cancer? 4. How can we explain this change in the risk of a person developing cancer? (Reference: Ch. 10)

8.  Active Reading  Underline important points.  Take notes in the margins.  Circle anything you are unfamiliar with.

10. 1. What are some differences between Judy and Mariah that might make Judy more “at risk” for skin cancer than Mariah? 2. What observations did Judy make concerning her mole?

11. JudyMariah

12. Characteristics of Mole ABCDE’s of Self Examination A-Asymmetry B-Border irregularity C-Color D-Diameter E-Elevation