1. Lipids (McM chapt 27) Naturally occuring, lipophilic comp. Wax, fat oils Soaps Phopholipids Prostaglandins Terpenoids Stereoids Wax, fat, oils: Derivatives of fatty acids ( carboxylic acids) Wax: esters between fatty acid and long chain alchohol

2. Fat (solid), oil (liquid) - Soaps Basic ester hydrol. - Saponifications Ca 2+ - “Hard water” Ca(OCOR) 2 (s) Cationic soaps

3. Phospholipids

4. Prostaglandins etc Subtypes COX COX-1: Synth of essential prostagland. COX-2: Active only under inflamations Rofecoxib Vioxx® Avreg 2004 COX2/COX2: 35 COX2 inhibitors Coxibes

5. Terpenoids C-10: Monoterpenes C-15: Sesquiterpenes C-20: Diterpenes C-25: Sesterterpenes C-30: Triterpenes

7. Stereoids B / C og C / D always trans Sex Hormones

8. Estrogens Corticostereoids Mineralcorticoid Aldosterone Regulation of elektrolyttic ballance increase re-uptake of Na (and hence H 2 0) Glucocorticoid Effect on metabolism (karbohydrates, lipids, proteins) Antiinflammatoric Numerous semisynth. analogs as drugs Various antiinflam. activity, mineralcorticoid side effects

9. Corticostereoids Mineralcorticoid Aldosterone Regulation of elektrolyttic ballance increase re-uptake of Na (and hence H 2 0) Glucocorticoid Effect on metabolism (karbohydrates, lipids, proteins) Antiinflammatoric Numerous semisynth. analogs as drugs Various antiinflam. activity, mineralcorticoid side effects