1. FDA/CVM/ONADE Swine Mycoplasma Pneumonia Workshop William L. Hollis, D.V.M. Kansas City, MO March 7, 2002 hollis@hogvet.com

2. Disclaimer!! Speaking for myself and my clients 4 different Answers CVS is a 100% swine practice. CVS does dispense therapeutics CVS –Dr. Joe Connor –Dr. James Lowe –Dr. Sarah Probst –Dr. Bill Hollis

3. Disease Presentation Chronic non-productive cough Decreased growth rate Low mortality High morbidity Increase in culls and lights

4. Clinical presentation Chronic –MOST COMMON –Severe Economic consequences –Requires interventions pig flow ventilation air quality vaccination strategic therapeutics Acute –RARE –Much worse with mixed bacterial infection –Mortality increases –More simple to solve

5. Focus on the important stuff Chronic –MOST COMMON –Severe Economic consequences –Requires interventions pig flow ventilation air quality vaccination strategic therapeutics

6. How do we know it’s Mycoplasma ? First time….. –Necropsy (3-5 pigs with consistent gross lesions) –Histology –Serology (10-30 per age group) Each group that follows –PIG FLOW PIG FLOW PIG FLOW –Serology –Slaughter checks

7. Pig Flow Ask questions first and diagram movements... –Sow farm segregation from growing pigs? –Multiple ages of growing pigs in same building? –Multiple ages of growing pigs on same site? –Age at movements? –Current prevention/treatment protocol?

11. On farm clinical picture Cough in 20-40% with slow movement from pen to pen Cough is deep With or without nasal discharge (if mixed) Necropsy 3-5 looking for similar gross lesions Discuss movements, history, and other groups Draw serum from 10-30 head

12. Why is economics important? We are a food producing industry. Agriculture is an old industry with narrow margins of profit and large capital investment. Production brings us back to the individual animal…....cost per pig

13. Cost of Losses in Efficiency

15. Not just Feed Only costs Feed only assumes they all still eat Assumes growth rate will be maintained Decision risk and unknown lies within the cost of light animals (premarkets) and cull animals (sort losses)

16. Opportunity Loss Equation

17. So then, What do I do about it? Eliminate? –Pig Density –Trusted/Monitored source Vaccinate? –Facility design and labor mangement Treatment and Control

18. Reduce individual animal suffering Prevent predictable population based disease V

19. Treatment and Control Options Pasteurella pneumonia (in 100% of herds) –Chlortetracycline –Oxytetracycline –Tiamulin Mycoplasma (in 98% of our herds) –Lincomycin Actinobacillus pleuropneumoniae (in 15%) –Tilmicosin

20. What’s it going to cost me? How big are the pigs? –usually in one of two groups 70lbs and 170-220lbs How long do we need to treat? –Most 14 days in the feed, although tilmicosin of course, is 21 day therapy

21. So then…What’s it going to cost me?

22. Well…What do you think I should do? No “blanket” protocol or policy… Treat for what you can see and measure Monitor with production records, feed budgets, and diagnostics. Reduce medication costs overall per pig

23. Thank you