1. Tom Furlani, Center for Computational Research University at Buffalo, October 15, 2015 Coexisting with Protected Health Information at CCR

2. Tom’s Guiding Principles to Storing HIPAA Data Avoid doing it if possible If not possible, find someone else to be responsible Be sure they are not housing your EMR data

3. PHI Data in CCR Treat them like a leper (just kidding) PHI racks isolated in CCR datacenter A distinct entity (IHI) Separate director and IT support staff Full time HIPAA compliance officer PHI racks in CCR isolated within a cage IHI card access separate from machine room access

4. >100Tb self-encrypting data repository with expansion capability 24x7 access control system, CCTV data center surveillance, and outside perimeter monitoring with video capture systems monitored by Roswell Park Security officers Security card reader access to facility, data center and IHI secured area 18 individually locked racks that are fully monitored for access, network, power, and cooling utilization Managed and Monitored Firewall Service, including vulnerability management services, real-time, 24x7x365 security event and log monitoring, analysis and response by Global Information Assurance Certification (GIAC) certified security analysts Encryption of data at rest and in motion Remote access via VPN only Virtual Desktop Infrastructure with no access to removable media Continuous antivirus and malware monitoring Segregated primary internet connection to the UB Fiber backbone IHI HIPAA-compliant security infrastructure

5. Institute for Healthcare Informatics (IHI) Data at the IHI includes:  UBMD Physicians’ Group: over 400 providers entering identified patient data over 6 years.  HealthNow: insurance claims on limited diagnosis over 7 years IHI Services  All services provided require strict security protocols and approvals by the institutional review board (IRB).  Services include data management, data aggregation, subject matter experts (SMEs), data modeling expertise and data warehousing.. IHI Data Hosting  Provide secure computing infrastructure to host researchers data.

6. IHI Clinical Data Repository (CIDR) 1,700,000 Patient records 59,000,000 claims 115,870,000 diagnosis 42,600,000 prescriptions 4,850,000 observations >1,000,000 million lab results

7. High Performance Computing Center for Computational Research Genomics, Proteomics & Bioinformatic Resources NYS Center of Excellence and Life Science Healthcare Data and Analysis Institute for Healthcare Informatics Tying It All Together at UB Clinical data, Genomic data, and computing horsepower

8. The non-PHI Side: UB’s Genomics, Bioinformatics and HPC Capabilities Research Scientists/ Industry Partners UB Next-Gen Sequencing: data generation and bioinformatics analysis Center for Computational Research  170 Tflops Total Aggregate Compute Capacity  11,400 cores; including $1.2M ESD CFA Award – HPC Cluster for Economic Dev  3.2 PB of High Performance Storage (GPFS)  Major Upgrades Planned for 2015  ~0.5 Tbyte of data a day  300 Billion sequence bases a day  100 human genomes a day UB Next-Gen Bioinformaticians computing on CCR resources