1.  DR A. T, ATANDA BAYERO UNIVERSITY/AMINU KANO TEACHING HOSPITAL, KANO

2.  Developed countries: progressive decline in the incidence of prostate cancer in the last decade  Developing countries: Paucity of data in this regard from developing countries of West Africa.  This study of 10-year data emanating from a Cancer Registry in Nigeria aims to add to available data.

3.  Data from Kano Cancer Registry on all biopsy validated prostate cancer cases were retrieved and analyzed for age distribution, age-adjusted incidence rate and tumor grade.

4.  2004 – 2013 studied  626 CaP  11.2% of all cancers and  23.9% of all male cancers  The ages ranged from 30 to 122 years with mean of 67.2±10.6 years.  It ranked 1 st among male and 3 rd among all cancers.

5.  The Age-standardized rate was 26.4 per 100,000 population and  rates increased progressively from the 4 th decade to the 7 th and over,  increase in incidence rate of 37.6% between 2004 -2008 and 2009-2013. crude increase of 221%

6.  Gleason scores 5 – 6, accounted for 37.7%  ≥70 years, high grade tumors were more frequent (p = 0.003018).

7. Age Range2004 – 20082009 – 2013Total ≤ 40325 40 – 49171229 50 – 594783130 60 – 6956162218 ≥7052142194 Unspec203050 195431626

8. Ages No of prostate cancers Total male cancers % of total male cancers Person years at risk Standard world population Age SIR <4047650.52 4,129.687 68,0000.07 40 – 49113323.3 354,573 12,0000.4 50 – 596243114.4 211,801 9,0002.6 60 – 6919653236.8 115,869 7,00011.8 70+30855855.2 107,438 4,00011.5 581 (626) 2,61819.8 (22.2)4,919,368100,00026.37

10.  Prostate Cancer (C61): 1975-1977 to 2008-2010 European Age-Standardised Incidence Rates per 100,000 Population, by Age, Great Britain Please include the citation provided in our Frequently Asked Questions when reproducing this chart: http://info.cancerresearchuk.org/cancerstats/faqs/#How Prepared by Cancer Research UK - original data sources are available from http://www.cancerresearchuk.org/cancer-info/cancerstats/

11. SEERS DATA

12. Gleason Score Number of cases % 2 – 415828.9 5 – 620637.7 7 – 1018333.4 547100

13. Age range Gleason score 2 – 4 Gleason score 5 – 6 Gleason score 7 – 10 ≤40IncompleteincompleteIncomplete 40 – 49Incompleteincomplete22 50 – 5926191055 60 – 69446647157 70+7198109278 141183168492

14.  In disparity to data from developed countries there is an increase in incidence rate for prostate cancer among Nigerian men,  higher grade tumors are more frequent among the elderly.  There is need for institution of a national screening program.