1. TASHKENT MEDICAL ACADEMY Department of Bioorganic and Biological Chemistry Bioorganic chemistry I COURSE SUBJECT : Alkaloids and Vitamins LECTURE №18 LECTURER : PROFESSOR A.D.DZHURAEV

2. PURPOSE OF LECTURES: Form of knowledge of the principles classification and structure important properties of alkaloids and vitamins as the chemical basis of for further orientation medicinal alkaloid nature and vitamins

3. The questions of: 1.Alkaloids 1.1. Alkaloids of pyridine and piperidine 1.2. Quinoline alkaloids group 1.3. Phenanthrene alkaloids - isoquinoline 1.4. Alkaloids of purine 1.5. Tropane alkaloids group 1.6. Isoquinoline alkaloids group 1.7. Indole alkaloids group 1.8. Alkaloids of Phenylethylamine

4. The questions of 2. Vitamins 2.1. Water-soluble vitamins 2.1.1. Vitamin B1 (thiamine). 2.1.2. Vitamin B2 (riboflavin). 2.1.3. Vitamin B6 (adermin, pyridoxine). 2.1.4. Vitamin B12 (antianemik, cyanocobalamin). 2.1.5. Foul acid. 2.1.6. Vitamin C. 2.2. vitamin-like substance 2.2.1. Para-aminobenzoic acid. 2.2.2. Vitamin B15 (pangamic acid). 2.2.3. Inositol. 2.2.4. Lipoic acid.

5. Classification alkaloids 1. GROUP pyridine and piperidine 2. GROUP quinoline 3. GROUP phenanthrene - isoquinoline 4. GROUP Purina 5. GROUP tropane 6. GROUP isoquinoline 7. GROUP indole

6. Alkaloids pyrrolidine derivatives, pyridine, piperidine gigrin nicotine coniine tropane anabasine piperidine halkasi pyrrolidine halkasi

7. Tropane derivatives cocaineatropine

8. Piperidine derivatives piperine lobeline

9. Quinoline derivatives quinine morphine heroin

10. Isoquinoline derivatives papaverine codeine

11. CLASSIFICATION OF VITAMINS I. Water-soluble vitamins 1. Vitamin B1 (thiamine). 2. Vitamin B2 (riboflavin). 3. Vitamin B6 (adermin, pyridoxine). 4. Vitamin B12 (antianemik, cyanocobalamin). 5. Foul acid. 6. Vitamin C. II. Fat-soluble vitamins 1 Vitamin A 2. vitamin D 3. vitamin E 4. vitamin K 5. vitamin F III. vitamin-like substance 1. P-aminobenzyl acid. 2. Vitamin B15 (Pang acid). 3. Inositol. 4. Linden acid.

12. VITAMINS HCL salt of Vitamin B1 or Thiamin

13. Vitamin B2 or riboflavin

14. piridoksol pyridoxal pyridoxamine Vitamin В 6

15. Folic acid folic acid

16. ASCORBIC ACID tautomerism vitamin С Keto acid Gulon L - sorbose

17. vitamin-like substance p-aminobenzyl acid.

18. vitamin В 15 (pangamic acid)

19. Inosite

20. lipoic acid dihydrolipoic acid