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Evolutionary analysis of hepatitis C virus gene sequences from 1953 by Rebecca R. Gray, Yasuhito Tanaka, Yutaka Takebe, Gkikas Magiorkinis, Zelma Buskell,

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Presentation on theme: "Evolutionary analysis of hepatitis C virus gene sequences from 1953 by Rebecca R. Gray, Yasuhito Tanaka, Yutaka Takebe, Gkikas Magiorkinis, Zelma Buskell,"— Presentation transcript:

1 Evolutionary analysis of hepatitis C virus gene sequences from 1953 by Rebecca R. Gray, Yasuhito Tanaka, Yutaka Takebe, Gkikas Magiorkinis, Zelma Buskell, Leonard Seeff, Harvey J. Alter, and Oliver G. Pybus Philosophical Transactions B Volume 368(1626):20130168 September 19, 2013 ©2013 by The Royal Society

2 Evolutionary analysis of HCV subgenomic sequence fragments obtained from blood sampled in 1953. Rebecca R. Gray et al. Phil. Trans. R. Soc. B 2013;368:20130168 ©2013 by The Royal Society

3 Results of the tip-dating analyses for the two 1953 sequences and four target reference sequences. Rebecca R. Gray et al. Phil. Trans. R. Soc. B 2013;368:20130168 ©2013 by The Royal Society

4 Estimates of the epidemic history of HCV subtype 1b in the USA. (a) Estimated mean evolutionary rates with 95% CIs (vertical bars). Rebecca R. Gray et al. Phil. Trans. R. Soc. B 2013;368:20130168 ©2013 by The Royal Society


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