1. CARDIOVASCULAR SYSTEM HEART

2. General Closed System -Blood Remains in Blood Vessels & Heart Double System -Four Chambers (Separation of Oxygenated & Deoxygenated Blood) -Each Side Supplies Different Circuit: *Pulmonary Circuit (R. Heart  Lungs  Heart) *Systemic Circuit (L. Heart  Body Tissues  Heart)

4. Heart – Size & Location Size: Adult Clenched Fist Position: Mediastinum, 2/3 to Left of Midline Relationships to Other Organs: -Deep to Sternum -Superior to Diaphragm -Medial to Lungs -Anterior to Esophagus, Descending Aorta

7. Heart – Surface Anatomy Sulci -Grooves, Indicate Boundaries of Chambers -Coronary Sulcus (Between Atria & Ventricles) -Interventricular Sulci (Between Ventricles) Apex (Inferior, Pointed Tip) Base (Posterior surface; formed by atria, mostly left)

9. Heart - Chambers Atria (2) -Superior Receiving Chambers (From Veins) -Auricles (ear-like flaps) -Right Atrium: *O 2 Poor Blood From Venae Cavae & Coronary Sinus -Left Atrium: *O 2 Rich Blood From Pulmonary Veins of Lungs

12. Heart – Chambers continued Ventricles (2) -Inferior Pumping Chambers (to Arteries) -Receive from Atria -Right Ventricle: *O 2 Poor Blood from Rt Atrium to Pulmonary Arteries (Pulmonary Circ.) -Left Ventricle: *O 2 Rich Blood from Left Atrium to Aorta (Systemic Circ.)

14. Heart - Septa Internal Walls Separate Chambers 2 Septa: -Interatrial Septum -(Between the Atria) -Interventricular Septum -(Between the Ventricles)

15. Heart - Valves One-Way, Direct Blood Flow Passive; blood pushes them open & closed 2 Pairs: -Atrioventricular (Cuspid) Valves *Between Atria & Ventricles *Prevent blood flowing back into atria  Tricuspid (Right)  Bicuspid (Left)

17. Atrioventricular Valves cont. *AV Valves are anchored to structures in the ventricles:  Chordae Tendineae Strong, Fibrous Strings Prevent Cusp Eversion  Papillary Muscle Conical Extensions of Myocardium in Ventricles Contract & pull on chordae tendineae

19. Heart - Valves -Semilunar Valves *Between Ventricles & Arteries *Prevent blood from back flow into ventricles  Pulmonary Semilunar Valve (Right)  Aortic Semilunar Valve (Left)

21. Heart - Wall 3 Layers: -Endocardium (Inner) *Endothelium *Lines Chambers, Valves, Septa, Blood Vessels -Myocardium (Middle) *Thickest Layer (Esp. in Left Ventricle!) *Cardiac Muscle Tissue *Inherent Rhythmicity

22. Heart Wall

23. Heart – Wall continued -Epicardium (Outer) *Visceral Pericardium *Serous Membrane *Thin, Fibrous, Transparent

24. Fibrous Skeleton Between atria & ventricles Dense regular C.T. Encircle valves & great arteries Attachment for cardiac muscle Electrical insulation between atria & ventricles Stabilizes valves

25. Heart – Pericardial Sac Encloses Heart & Bases of Great Vessels Composed of 2 layers: -Parietal Pericardium *Inner serous coat of sac *Secretes lubricating pericardial fluid into *Pericardial cavity (space between serous layers)

28. Heart – Pericardial Sac continued -Fibrous Pericardium *Outer, fibrous coat of sac *Tough, protective *Reinforces serous coat

29. CARDIAC CYCLE Events of one heartbeat: -Systole *Atria Contract, Ventricles Fill *Ventricles Contract, Blood Forced into Aorta and Pulmonary Trunk -Diastole *Atria Relax & Fill *Ventricles Passively Receive Blood from the Atria

31. Cardiac Output Stroke Volume (SV) -Volume of blood pumped out by ventricle each heartbeat -70ml/beat Cardiac Output (CO) -Volume pumped out by ventricle in 1 minute -CO = Heart Rate x Stroke Volume -75 b/min x 70 ml/beat = over 5,000 ml/min

32. Factors Influencing Cardiac Output Venous Return directly effects Stroke Volume (& CO) Heart Rate (& CO) is effected by drugs, hormones & ions

33. BLOOD PRESSURE BP = pressure blood exerts on inner blood vessel walls BP rises & falls in response to heart contraction & relaxation BP keeps blood moving between heart contractions

34. BLOOD PRESSURE Systole (contraction of the heart) -Contraction of ventricles causes arterial pressure to rise -Systolic pressure (SBP) is the maximum pressure during contraction

35. BLOOD PRESSURE CONTINUED Diastole -Relaxation and refilling of ventricles while semilunar valves are closed -Arterial pressure drops as blood flows “downstream” -Diastolic pressure (DBP) is the minimum pressure just before the next systole

37. Average BP = less than 120/80 Arterial surge in pressure = Pulse Pulse rate usually = heart rate Average adult pulse = 60-80 BPM

38. CONDUCTION SYSTEM OF THE HEART Specialized Cardiac Muscle Tissue Capable of Generating & Conducting Action Potentials Stimulates Contraction of Myocardial Tissue Sets basic rhythm of the heart

39. CONDUCTION SYSTEM OF THE HEART continued 5 Components: -Sinoatrial Node (Pacemaker) *Right Atrium *Spontaneously Depolarizes *Activates Atrial Contraction *Origin of Heart Beat *Action Potential Spreads to Atrial Myocardium &:

40. CONDUCTION SYSTEM OF THE HEART continued -Atrioventricular (AV) Node *Rt. atrium (interatrial septum) *Action potential spreads to: -Atrioventricular Bundle (Bundle of His) *Only electrical pathway between atria & ventricles (C.T. Block) *Carries action potential through interventricular septum to:

41. CONDUCTION SYSTEM OF THE HEART continued -Bundle Branches (Left & Right ) *Interventricular septum *Carries action potential toward respective ventricles -Purkinje Fibers *Myocardium of ventricles *Conduct action potentials to ventricular myocardium

43. C. T. Blocks Action Potentials Between Atria & Ventricles

44. Moderator Band (Septomarginal Trabecula)

45. ELECTROCARDIOGRAM (ECG/EKG) Record of Electrical Changes in Heart Muscle Electrical Changes due to Depolarization & Repolarization of Cardiac Muscle Fibers Metal Electrodes Applied to Skin, Attached to Physiograph, Pick-up Electrical Activity Normal Cardiac Cycle Gives Rise to Characteristic “Waves”

46. ELECTROCARIDOGRAM (ECG/EKG) continued P Wave -SA Node Stimulates Atrial Depolarization -Occurs Prior to Atrial Contraction QRS Complex -Ventricular Depolarization -More Tissue, More Electrical Activity, Larger Wave -Occurs Prior to Ventricular Contraction T Wave -Ventricular Repolarization

48. EKG ABNORMALITIES Tachycardia (BPM>100) Bradycardia (BPM<60) Premature Beats (Ectopic Source) Flutter (BPM 250-350) Fibrillation (Rapid, Uncoordinated)

49. HEART SOUNDS Caused by Closing of Heart Valves AV Valves -prevent blood from flowing backwards into atria -“Lubb” Semilunar Valves -prevent blood from flowing backwards into ventricles -“Dupp”

50. HEART MURMURS Abnormal sound Often indicates valve disorder Causes: -Congenital defects -Scarring -Insufficiency/Backflow