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  Insecticides: Household and agricultural  Nerve gas: Warfare weapon  Led to development of Alzheimer’s treatments  Jet oil Where Can They Be Found?

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Presentation on theme: "  Insecticides: Household and agricultural  Nerve gas: Warfare weapon  Led to development of Alzheimer’s treatments  Jet oil Where Can They Be Found?"— Presentation transcript:

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2   Insecticides: Household and agricultural  Nerve gas: Warfare weapon  Led to development of Alzheimer’s treatments  Jet oil Where Can They Be Found?

3   Produced by the reaction of alcohols and phosphoric acid  They are lipophilic- fat loving  Organic compounds  What does organic mean? Chemistry

4   Organophosphates can accumulate in the fats of humans and animals causing toxic poisoning. The metabolites are even more toxic.  Veterans and agricultural workers are most often affected. Here’s the Truth

5   Organophosphates can disrupt signals in the brain.  Its all about the nervous system! Why Are Organophosphates Toxic?

6   Neuron : A cell that transmits electrical or chemical signals in the body  Neurotransmitter : A chemical that sends a signal from one neuron to another  Synapse : The connection in between neurons where neurotransmitters pass. Vocabulary to Know

7   Acetylcholine: A neurotransmitter involved in transmission of signals that regulate muscle stimulation, learning and memory.  Acetylcholinesterase: An enzyme that degrades acetylcholine (substrate).  Why might this be important? Acetylcholine and Acetylcholinesterase


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