1. Group 4 3-C Marcelo, Pamela – Mendoza, Gracielle

2. Interpret a (+)HBeAg, anti-HBcAg, and/or anti-HCV test.
Indicates that virus is replicating & the infected individual has high levels of HBV
(+) anti-HBcAg
Indicates previous or ongoing infection with HBV
(+)anti-HCV test
Indicates past or present HCV infection

3. Laboratory Exams for Muscle Weakness
Associated Causes of Primary Muscle Weakness
Electrolyte
Hyponatremia, hyperkalemia
Hypocalcemia
Adrenal Insufficiency
Secondary Hyperparathyroidism
Enzyme Studies
Elevated transaminases and GGT
Creatine Kinase
Elevated
Normal to Elevated
Alcohol
Dermatomyositis, Inclusion body myositis, Polymyositis, Becker Muscular Dystrophy
Alcohol, Hyperthyroidism, Rheumatoid Arthritis, SLE
Aaron Saguil..Madigan Army Medical Center, Tacom a, Washington. Vol 71. no
American Family Physician Website

4. ACTH assay, ACTH stimulation test
Hormone Studies
ACTH assay, ACTH stimulation test
Urine free cortisol, dexamethasone suppression test,
CRH stimulation test
Elevated T3, T4,
Elevated TSH
Adrenal insufficiency
Glucocorticoid excess
Hyperthyroidism
Hypothyroidism
Serologic Tests
(+) ANA
Anti- DNA, depressed C3 and C4
elevated RF factor
Dermatomyositis, Polymyositis
SLE
Rheumatoid arthritis
CBC, RBC indices --> Anemia
Decreased Vitamin B12
Alcohol
Elevated Myoglobin
Dermatomyositis, Inclusion body myositis, Polymyositis
Aaron Saguil..Madigan Army Medical Center, Tacom a, Washington. Vol 71. no
American Family Physician Website

5. 1990 Criteria For the Classification of Polyarteritis Nodosa (at least 3)
1. Weight loss of 4 kg or more
2. Livedo reticularis
3. Testicular pain or tenderness
4. Myalgias, weakness or leg tenderness
5. Mononeuropathy or polyneuropathy
6. Diastolic BP >90 mm Hg
7. Elevated BUN or creatinine
8. Hepatitis B virus
9. Arteriographic abnormality
10. Histologic changes in biopsy of small or medium-sized artery containing PMN
American College of Rheumatology Criteria For the Classification of Polyarteritis Nodosa . Retrieved Aug 25, from .

6. Negligible side effects Interferon
DRUG
SIDE EFFECT
Lamivudine
Negligible side effects
Interferon
Flu like symptoms, marrow suppression, autoimmune reactions (autoimmune thyroiditis) and others such as alopecia, rashes diarrhea and numbness and tingling of extremities
Adefovir
Increased creatinine, hematuria, Weakness, headache, fever, cough, nausea and vomiting, diarrhea
Pegylated Interferon
flu-like syndrome, headache, fatigue, myalgia and local reaction at the injection site
Entacavir
Rashes
Harrison’s Principles of Medicine 17th ed.
The safety of pegylated interferon alpha-2b in the treatment of chronic hepatitis B: predictive factors for dose reduction and treatment discontinuation, M. van Zonneveld, et al.