1. © Cancer Research UK 2006 Registered charity number 1089464 Table One: Numbers and rates of new cases for malignant melanoma, UK by country, 2006 EnglandWalesScotlandN.IrelandUK Cases Males4,0092424451074,803 Females4,6492635431525,607 Persons8,65850598825910,410 Crude rate per 100,000 population Males16.116.818.012.516.2 Females18.017.320.517.118.1 Persons17.117.019.314.917.2 Age-standardised rate (European) per 100,000 population Males14.214.115.512.414.3 95% CI13.814.612.315.914.117.010.014.713.914.7 Females15.413.916.915.515.4 95% CI14.915.812.315.615.518.313.018.015.015.8 Persons14.714.016.013.914.7 95% CI14.415.012.715.215.017.012.215.614.415.0

2. © Cancer Research UK 2006 Registered charity number 1089464 Figure One: Percentage distribution of malignant melanoma on parts of the body

3. © Cancer Research UK 2006 Registered charity number 1089464 Figure Two: Numbers of new cases and age specific incidence rates, by sex, malignant melanoma, UK 2006

4. © Cancer Research UK 2006 Registered charity number 1089464 Figure Three: Melanoma incidence by health authority, males, UK and Ireland, 1991-1999

5. © Cancer Research UK 2006 Registered charity number 1089464 Figure Four: European age-standardised* incidence rates, malignant melanoma by sex, EU, 2002 estimates * to the European standard population

6. © Cancer Research UK 2006 Registered charity number 1089464 Figure Five: World age-standardised* incidence rates, malignant melanoma, by sex, 2002 estimates * to the European standard population

7. © Cancer Research UK 2006 Registered charity number 1089464 Figure Six: Age-standardised* (European) incidence rates, malignant melanoma, by sex, Great Britain, 1975-2006 * to the European standard population

8. © Cancer Research UK 2006 Registered charity number 1089464 Figure Seven (a): Age-specific incidence rates, malignant melanoma, males, Great Britain 1975-2006

9. © Cancer Research UK 2006 Registered charity number 1089464 Figure Seven (b): Age-specific incidence rates, malignant melanoma, females, Great Britain 1975-2006

10. © Cancer Research UK 2006 Registered charity number 1089464 Figure Eight: Solar UV Radiation in relation to the Earth and ozone layer

11. © Cancer Research UK 2006 Registered charity number 1089464 Table Two: Age-standardised incidence rates* per 100,000 population for malignant melanoma, by race and sex, 1998-2002, USA MalesFemales All races21.814.0 White25.917.2 Hispanic4.54.4 Asian/Pacific Islander1.81.6 Black1.30.8 *standardised to the 2000 US Std Population

12. © Cancer Research UK 2006 Registered charity number 1089464 Figure Nine: Percentage of men and women who used a sunbed or tanning machine in the past 6 months, Great Britain, 1999

13. © Cancer Research UK 2006 Registered charity number 1089464 Table Three: Categories of people who should not use sunbeds as recommended by WHO

14. © Cancer Research UK 2006 Registered charity number 1089464 Table Four: Skin phototype

15. © Cancer Research UK 2006 Registered charity number 1089464 Table Five: Seven point checklist for pigmented lesions Major featuresMinor features change in sizeinflammation irregular pigmentationitch/altered sensation irregular borderlesion larger than others oozing/crusting

16. © Cancer Research UK 2006 Registered charity number 1089464 Table Six: Tumour thickness, excision margins, survival and follow-up Thickness of tumourExcision marginsApproximate 5 year survivalFollow-up In situ2-5mm>95%One follow-up Less than 1mm1cm>95%3 monthly for 3 years 1-2mm1-2cm80-90%3 monthly for 3 years 2-4mm2-3cm (2cm preferred)60-75%then 6 monthly for Greater than 4mm2-3cm30-50%a further 2 years

17. © Cancer Research UK 2006 Registered charity number 1089464 Figure Ten: Five-year age-standardised* survival for patients aged 15-99 diagnosed with malignant melanoma, by sex, England and Wales, 1971-2006 * to the European standard population

18. © Cancer Research UK 2006 Registered charity number 1089464 Figure Eleven: Five-year survival by tumour thickness, patients diagnosed 1979-1998, by sex, Scotland

19. © Cancer Research UK 2006 Registered charity number 1089464 Figure Twelve: Age-standardised* five-year relative survival rate, by age, malignant melanoma, by sex, England and Wales, 2001-2006 * to the European standard population

20. © Cancer Research UK 2006 Registered charity number 1089464 Table Seven: Numbers of deaths and rates for malignant melanoma, UK by country, 2007 EnglandWalesScotlandN.IrelandUK Deaths Males9236394241,104 Females787507031938 Persons1,710113164552,042 Crude rate per 100,000 population Males3.74.33.82.83.7 Females3.03.32.63.53.0 Persons3.33.83.23.13.3 Age-standardised rate (European) per 100,000 population Males3.13.43.12.63.1 CI 95%2.93.32.64.22.53.81.53.62.93.3 Females2.12.41.82.72.1 CI 95%2.02.31.73.01.42.21.73.62.02.3 Persons2.62.82.42.6 CI 95%2.52.72.33.42.02.71.93.32.52.7

21. © Cancer Research UK 2006 Registered charity number 1089464 Figure Thirteen: Numbers of deaths and age-specific mortality rates by sex, malignant melanoma, UK, 2007

22. © Cancer Research UK 2006 Registered charity number 1089464 Figure Fourteen (a): Age-specific mortality rates, malignant melanoma, males, UK, 1971-2007

23. © Cancer Research UK 2006 Registered charity number 1089464 Figure Fourteen (b): Age-specific mortality rates for malignant melanoma, females, UK, 1971-2007