1. Review Bacteria Normal Flora The Magic Bullet, Antibiotics and Antibiotic Resistance Koch’s Postulates The Immune System --including the inflammatory response Balanced Polymorphism Food Poisoning Many Technical Terms Drugs

2. Why was it possible to eradicate Small Pox from the face of the earth but not, influenza?

3. Smallpox has been eradicated, polio is next and half a dozen other diseases are targeted for elimination. Vaccines protected 8/10 of the world’s children (WHO report).

4. Pathogen Transmission Symptoms Vectors Alternative Hosts Prevention Treatment Measles AIDS Chicken Pox Influenza

5. Arbovirus Exantheme Enterovirus Respiratory viruses How are Viruses Classified?

6. This is an Alphavirus, one of the best known model systems among enveloped viruses. The RNA genome (red) is packaged into a nucleocapsid (orange for the capsid proteins), which is surrounded by a lipid bilayer (green) with transmembrane spike proteins (blue).

7. Measles. Worldwide, almost 1 million children die of measles each year. In the United States, after a long decline, the number of measles cases started to rise in the late 1980s when there was a drop in the number of children being vaccinated against the disease.

8. Measles Pathogen: An exantheme virus Same as distemper in dogs High fever, runny nose, red eyes, spots, sensitivity to light

9. Pathogen Herpes-zoster Transmission Person-to-person Symptoms Chicken Pox and Shingles Prevention VaccineChickenPox

10. Herpes Viruses

11. Herpes Simplex--Type 1 causes fever blisters and red eye no cure; usually not life threatening but, can lead to blindness; rarely causes brain inflammation; stress causes reoccurrence

12. Herpes Simplex--Type 2 Herpes Zoster Epstein-Barr Viruses (associated with mononucleosis) (associated with mononucleosis)

13. In what way are each of the following antibiotics a “magic bullet”? Penicillin Tetracycline Sulfa drugs

14. Outline Koch’s Postulates

15. Koch's postulates 1. The microbe must be present in every case of the disease and not present in healthy animals 2. It must be isolated and grown in a pure culture

16. 3. The same disease must result when the isolated microbe is inoculated into a healthy host 4. The same microbe must be isolated again from the diseased host

17. List at least 4 factors associated with increased risk of contracting an infectious disease.

18. How are ducks, pigs, and China associated with the flu?

19. Name and describe at least 3 kinds of food poisoning: