1. Coronary Stents  A stent is a support device for permanent expansion of blood vessel to restore blood flow.  Implantation is done with X-ray guidance in a Cathlab, which exposes the patient to ionizing radiation and potentially kidney damaging X-ray contrast agents.  After implantation, there is currently no way to show a potential restenosis (re-narrowing) of the blood vessel using non-invasive diagnostic systems. Diagnosis requires another catheterization procedure. Stent Implantation Biophan’s technology presents an alternative – using an MRI system for diagnosis of restenosis. MRI diagnosis provides advantages, since it is non-invasive and uses no harmful radiation and no iodine contrast agents.

2. 1.5 Tesla MRI Artifacts of Current Stents Expanded Stents Original size Crimped Stents Cobalt 316L stainless steel With existing stent technology, no useful images can be obtained from within common stents using MRI.

3. Imaging of In-Stent Blood Clots Using Biophan Resonator Technology 1 Tesla Philips NT, head coil, TR=300ms, TE=6ms, FA=40°, transversal Cross Sectional Schematic of Stent with blood clot Video Biophan’s technology enables imaging of the blood clot within the stent Resonant StentBlood Clot