1. Drug Interactions Additive Interaction: occurs when medicines work together in a positive way. Additive Interaction: occurs when medicines work together in a positive way. Can you think of an example? Can you think of an example? Answer: an anti-inflammatory and a muscle relaxant prescribed to treat join pain. Answer: an anti-inflammatory and a muscle relaxant prescribed to treat join pain. Synergistic Effect: an interaction of two or more medicines that results in a greater effect than when the meds are taken alone. Synergistic Effect: an interaction of two or more medicines that results in a greater effect than when the meds are taken alone. Explanation: one med may increase rate of digestion, enabling a second to be absorbed faster. Explanation: one med may increase rate of digestion, enabling a second to be absorbed faster.

2. Interactions continued Antagonistic Interaction: the effect of one medicine is canceled or reduced when taken with another medicine. Antagonistic Interaction: the effect of one medicine is canceled or reduced when taken with another medicine. Can you think of an example? Can you think of an example? Answer: organ transplant recipient takes Answer: organ transplant recipient takes anti-rejection meds, if recipient is diabetic and takes insulin, anti rejection drug will decrease effectiveness of insulin

3. Interactions cont. Answer: With tolerance the body becomes used to the effect of the medicine. The body then requires increasingly larger doses of the medicine to produce the same effect. Answer: With tolerance the body becomes used to the effect of the medicine. The body then requires increasingly larger doses of the medicine to produce the same effect. Cont: withdrawal will occur if there is a chemical dependence. Examples include cocaine and codeine and symptoms are: insomnia, severe headache, cramps, and chills. Cont: withdrawal will occur if there is a chemical dependence. Examples include cocaine and codeine and symptoms are: insomnia, severe headache, cramps, and chills. ***may require medical intervention. ***may require medical intervention.

4. General Terms OTC v. Prescription OTC v. Prescription Over the counter v. doctor recommended Over the counter v. doctor recommended Generic Generic Manufactured by a pharmacy/grocery store and costs less Manufactured by a pharmacy/grocery store and costs less What does medicine misuse mean? What does medicine misuse mean? Answer: failure to follow instructions listed on label or script. Deviating from intended use. Answer: failure to follow instructions listed on label or script. Deviating from intended use.

5. Marijuana A plant whose leaves, buds and flowers are usually smoked for intoxicating effects. A plant whose leaves, buds and flowers are usually smoked for intoxicating effects. Hashish or hash is a stronger form of Marijuana. Hashish or hash is a stronger form of Marijuana. Marijuana is NOT harmless. It is a mind altering drug. Marijuana is NOT harmless. It is a mind altering drug. Marijuana raises the level of dopamine= euphoric state. Marijuana raises the level of dopamine= euphoric state. Contains more cancer-causing chemicals than smoke and offers the same health risks. Contains more cancer-causing chemicals than smoke and offers the same health risks.

6. Marijuana Cont. Active ingredient= THC Active ingredient= THC THC is the main psychoactive ingredient in marijuana and is stored in body fat. THC is the main psychoactive ingredient in marijuana and is stored in body fat. Traces are present for as long as up to a month. Traces are present for as long as up to a month. Marijuana is in a category of is own. It is not considered a stimulant, depresant, narcotic or hallucinogen. Marijuana is in a category of is own. It is not considered a stimulant, depresant, narcotic or hallucinogen.