1. LifePak® Nano Workshop North America Leadership Conference March 3, 2006 This material has been prepared by Pharmanex to be used in conjunction with general educational events and activities only. Alterations or modifications of this presentation without the express approval of Pharmanex is prohibited.

2. One unique technology teamed with Two proprietary products drive One exclusive sponsoring story The Opportunity Simplified

3. Carsten R Smidt, Ph.D., FACN Vice President, Global Research & Development Pharmanex

4. Huzhou Mfr. Plant Shanghai R&D Center Beijing Clinical Center Provo, Utah Headquarters & Pharmanex Research Institute over 125 Scientists

6. Prof. Lester Packer

8. The Power of Nanotechnology

9. Nano-Switch

10. Nanotube Wires

14. What is Nanotechnology? 1.Size: 1 -100 nanometers –Most molecules are 1 to 100 nm in size 2.Function at the Molecular Level –Nanotechnology achieves new functionalities by molecular rearrangements

15. Reasons for Limited Absorption Poor intestinal solubility Requires fat for dissolution (e.g., Lipocarotenes) Aggregation into large particles –not easily digested and absorbed

16. The Nanotechnology Difference Pharmanex patent-pending & proprietary process Small nano-nutrients are easily dispersed and absorbed + nano-carbohydrate shell Coenzyme Q 10 nano-CoQ 10 = *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

17. NanoCoQ10™

18. NanoCoQ 10 5-fold increase in absorption! The Nanotechnology Difference

19. Intestinal LumenMucosa Cell (Intestinal Wall Cell) Cell Membrane nano-CoQ 10 Nano-Carbohydrate Shell CoQ 10

20. Nano-CoQ 10 Carotenoids? Nano-Carotenoids

22. lifepak ® nano Study Placebo lifepak nano ? 60+ Antioxidants Ongoing placebo-controlled clinical study

23. Nano- Carotenoids Nano-CoQ 10 Red Wine Polyphenols New Vitamin E Highly Effective Minerals

24. lifepak nano: 8 Formulas in 1 > Complete, Balanced and Convenient Multi Vitamin Mineral Anti- oxidant Formula Glucose Metabolism Formula Immune Nutrient Formula Bone Formula Cardio- Vascular Formula Anti Aging Formula

26. The New Dimension! For All Adults (age 18-121) Proprietary Science Broadest Health Benefits www.lifepaknano.com

27. Angela Mastaloudis, PhD Associate Senior Scientist R&D, Pharmanex Ph.D. Exercise Physiology Oregon State University M.S. Nutrition Science Oregon State University Society for Free Radical Biology and Medicine –Young Investigator Award Lester Packer –Young Investigator Award Linus Pauling Institute –Graduate Fellowship

28. New, broader-spectrum nano-carotenoid formula: –alpha-carotene –beta-carotene –lycopene –lutein –zeaxanthin (new): Eye health benefits* –astaxanthin (new): Inflammatory balance* as found in 5-10 fruits & vegetables per day *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. lifepak nano

29. Pharmanex Nanotechnology To increase intestinal uptake of poorly absorbed fat-soluble nutrients: –Carotenoids (lycopene, alpha+beta-carotenes, zeaxanthin, astaxanthin) –Coenzyme Q 10

30. = Better Bioavailability* = Increased Scanner Scores* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

31. Purpose How much more and how much faster does lifepak nano increase scanner scores than a placebo? OR PLACEBO

32. Study Design I Supplementation 52 Subjects were recruited and randomly assigned to groups Twice a day, with breakfast and with dinner, subjects took: –lifepak nano or –Placebo Study length: 18 weeks

33. Study Design II BioPhotonic Scanner Subjects were scanned a total of 15 times! Diet We encouraged to continue with their typical diet for the entire study

34. Results 42 out of 52 subjects completed the 18 week study

35. * * * * * * * * * Scanner Scores Increase with lifepak nano *p<0.05 between groups 45% Increase! 41% Increase! 37% Increase! 30% Increase! 19% Increase!

36. Scanner Scores Increase with lifepak nano *p<0.05 compared to wk 0 #p<0.05 compared to placebo #, * NSEGlobal Convention Convention

37. Scanner Scores Increase with lifepak nano *p<0.05 compared to wk 0 #p<0.05 compared to placebo #, *

38. Summary Lifepak nano increased scanner scores as fast as two weeks Scanner scores increased in all 20 subjects taking lifepak nano Lifepak nano increased scanner scores 18,000 units more than placebo in 18 weeks Even after 18 weeks scanner scores were still increasing in the lifepak nano group

39. Better Bioavailability* Faster and Higher Increases in Scanner Scores* = *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

40. The Power of Nanotechnology Visit our PRODUCT SHOWCASE!

41. Key Business Takeaways Nanotechnology increases absorption of poorly absorbed nutrients* First in industry to apply nanotechnology to a multivitamin supplement* Proprietary and patent-pending Guaranteed to increase SCS* Clinically proven ~ 18,000 increase Do You NANO? *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

42. www.lifepaknano.com

43. More Information Presentations www.pharmanexusa.com Leadership Conference link My Office  Marketing Tools Product Resources www.pharmanexusa.com www.pharmanexscanner.com www.lifepaknano.com Product Support E-Mail: productsupport@pharmanex.com Phone: 1-800-487-1000