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SICKLE CELL ANEMIA AND TYPES OF MUTATIONS Mutations.

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Presentation on theme: "SICKLE CELL ANEMIA AND TYPES OF MUTATIONS Mutations."— Presentation transcript:

1 SICKLE CELL ANEMIA AND TYPES OF MUTATIONS Mutations

2 Video: Sickle Cell Anemia http://www.youtube.com/watch?v=F3RHJcLYcm8

3 Discussion: Eddy Why did Eddy have Sickle Cell Anemia? What was different about Eddy’s red blood cells? What effects did this have on Eddy’s body? So what kind of mutation might have caused this???

4 Go to this website and play around with this game: http://www.nature.ca/genome/04/0413_e.cfm#010 Fill out the worksheet with a partner as you explore this activity

5 Class Discussion: Types of Mutations What type of mutation(s) seem to have no effect on your name?  How would this mutation affect protein synthesis in your body? What types of mutation(s) had little effect on your name?  How would this mutation affect protein synthesis in you body? What was the most serious type of mutation? Why?  How would this mutation affect protein synthesis in your body So what kind of mutation caused Sickle Cell Anemia in Eddy?

6 Small-Scale Mutations Point Mutations  Missense  Nonsense  Silent Insertion Deletion

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