1. Polypeptide Chain Synthesis: A Paper Simulation Actitivy

2. Proteins Are organic polymers. Polymers are composed of monomers.
A monomer is a repeating structural unit
What is the repeating structural unit for a protein?
The amino acid
Proteins

3. Basic Amino Acid Structure
Amino group
R group
Carboxyl group

4. The Twenty Amino Acids with the R group of each highlighted

5. Polypeptide Synthesis
Involves two amino acids.
Involves a dehydration synthesis.
Involves a chemical reaction that occurs between two specific areas of the amino acid.
Requires an –OH group and an –H from another –OH group
Polypeptide Synthesis

6. Think about these questions:
What is a polypeptide chain?
What two functional groups are involved in polypeptide synthesis?
How can water form during the synthesis of a polypeptide chain?

7. Is this a complete protein? No
Proteins are many chained structures.
Are organic polymers composed of monomers called amino acids. How many amino acids are in this chain?
Strands of amino acids are called polypeptide chains. Where are the peptide bonds?
Is this a complete protein? No

8. The complete protein is the picture with two polypeptide chains.
Amino Acids
Polypeptide Chain
Protein with two
Polypeptide chains
The complete protein is the picture with two polypeptide chains.

9. What determines a specific protein?
The sequence of amino acids determines the specific protein
Question 10 on the lab wants you to write the sequence of amino acids from the paper chain
Phe-met-tryp-ala
Use the (4) amino acids to make a protein
Tryp–phe–ala-met
Make another one:
Phe-tryp-met-ala
What determines a specific protein?

10. Video for Protein Function
Functions of Proteins