Presentation on theme: "The packaging of DNA in eukaryotic chromosomes or how you change this... 0.2-2 µm 4 cm Too small to show the real size, but you could fit 10,000 along."— Presentation transcript:
The packaging of DNA in eukaryotic chromosomes or how you change this µm 4 cm Too small to show the real size, but you could fit 10,000 along the length of a fingernail! The length of DNA in one chromosome into this...
Link to 3D animation of the packaging of DNA into chromosomes
Level 1: Nucleosomes or beads on a string Histone proteins form a complex Linker DNA
Level 2: Chromatin fibre Nucleosomes coil and stack
Level 3: Looped fibres Protein scaffold Chromatin fibre loops along the protein scaffold
Level 4: More folds to make the most compacted chromosome µm Looped chromatin fibre folds The most condensed form of DNA packaging during metaphase. Replication has just occurred so the image shows two chromatids