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The Environmental Genomics Thematic Programme Data Centre Dawn Field, Director.

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Presentation on theme: "The Environmental Genomics Thematic Programme Data Centre Dawn Field, Director."— Presentation transcript:

1 The Environmental Genomics Thematic Programme Data Centre Dawn Field, Director

2 Dawn Field dfield@ceh.ac.uk The Environmental Genomics Thematic Programme Funded by the NERC at £16.5m Aimed at understanding the molecular basis of evolutionary change, organismal phenotype, and ecosystem function Evolutionary and Ecological theory plus Genomic technologies Round 1 (17) funded in Sept, 2001, Round 2 to be funded in April 2003 Data Centre to be Launched October 2002 for a period of 5 years

3 Dawn Field dfield@ceh.ac.uk The Environmental Genomics Thematic Programme Programme http://www.nerc.ac.uk/funding/thematics/envgen/ Data Centre http://envgen.nox.ac.uk/ FOR MORE INFO...

4 Dawn Field dfield@ceh.ac.uk Data Management

5 Dawn Field dfield@ceh.ac.uk The Environmental Genomics Thematic Programme Data to be generated 25-30 Awardees producing genomic data non-model organisms microbes to vertebrates key area of overlap in data is microarray and EST data

6 Dawn Field dfield@ceh.ac.uk The Data Initiative Must comply with NERC data policy, balanced by science driven Awardee requirements: Heterogeneity and complexity of genomic data Emerging standards, especially for microarray data (MIAME, MAGE-ML) and beyond that proteomics and metabolomics) Importance of meta-data collection Emphasis on need for Local solutions Emphasis on need for bioinformatics training and skill development

7 Dawn Field dfield@ceh.ac.uk The Goals of the Data Centre The CEH Oxford EG Thematic programme Data Centre will provide the data warehouse for the Programme according to the requirements of the NERC Policy for data management. Working with Bioinformatics Partners to provide and develop specific file formats, analysis tools, and data archiving methods will allow the use of common software solutions that will maximise the value of the final data holding.

8 Dawn Field dfield@ceh.ac.uk Data Centre - Mission The mission of the EG Data Centre at CEH Oxford is to assure that: All Awardees have the means to collect and submit their data to the Centre We create the capacity and expertise within the Centre to collect, manage, distribute, protect, and exploit the collective data holdings All EG generated genomic data is eventually accessible long-term by the wider-community in an organised and add-value format We create the opportunity for affordable 'buy-in' options for future Research council-funded science initiatives Scale to meet future demand

9 Dawn Field dfield@ceh.ac.uk Data Centre - Mission We will implement this mission through the creation of: A Data Centre Team with expertise in bioinformatics, database management, and computing A computing infrastructure (hardware and software) that will include both centralised resources and a network of specialised computers in Awardee Labs

10 Dawn Field dfield@ceh.ac.uk Integration & Implementation

11 Dawn Field dfield@ceh.ac.uk Bioinformatics Partnerships Silicon Genetics http://www.silicongenetics.com/cgi/SiG.cgi/index.smf maxD http://bioinf.man.ac.uk/microarray/resources.html Nembase http://nema.cap.ed.ac.uk/nematodeESTs/nembase.html The Centre http://envgen.nox.ac.uk/ FOR MORE INFO...

12 Dawn Field dfield@ceh.ac.uk Centre Overview Bioinformatics Software Solutions GeneSpring/GeNet/ScriptEditor maxD (meta-data policies) Partial Genome Sequence Analysis Pipeline and Database System Bio-RedHat 7.3 (Custom Designed Linux Distribution for Bioinformatics Research that will include GeneSpring, Edinburgh's Partial Genome Sequence Tools, and maxD), Bioinformatics for the PC Toolkit (Unix Emulation for tools in Bio-RedHat 7.3)

13 Dawn Field dfield@ceh.ac.uk Centre Overview Location CEH Oxford (MAN, EDIN) Centre Team Bioinformatician, Data Manager, Linux Developer, Technical Administrator 4 Developers (MAN, EDIN) Computational Infrastructure Commodity Hardware running Linux, combination of open source and commercial software

14 Dawn Field dfield@ceh.ac.uk Centre Overview Community Development Web site, Mailing Lists, Help Desk(s), Discussion Boards, Presentations at EG Workshops Teaching and Training EGDC Documentation Project, Bio-RedHat Workshops, Bioinformatics Training in the context of supported software and access to total data holdings, 8 EPSRC/BBSRC MRes /DPhil placements

15 Dawn Field dfield@ceh.ac.uk Centre Overview Data Holdings microarray data repository (GeNet) EST sequence warehouse Bio-IT and Knowledge-based Tangibles Bio-Linux Extensive Documentation Archive (FAQ, Links, Installation and usage documents) Data Centre “Toolkit”

16 Dawn Field dfield@ceh.ac.uk Centre Overview: Future Centre Funded labs GeNet microarray repository EST sequence warehouse GeneSpring microarray analysis software EST pipeline Bio-Linux Bio-PC recipes Software HELP files Help Desk

17 Dawn Field dfield@ceh.ac.uk Centre Overview: Sept 2002 Centre Funded labs Bio-Linux Bio-PC recipes www GeNet microarray repository Software HELP files Help Desk

18 Dawn Field dfield@ceh.ac.uk Centre Overview: Oct 2002 Centre Funded labs GeNet microarray repository GeneSpring microarray analysis software Bio-Linux Bio-PC recipes Software HELP files Help Desk

19 Dawn Field dfield@ceh.ac.uk Centre Overview: winter Centre Funded labs GeNet microarray repository EST sequence warehouse GeneSpring microarray analysis software EST pipeline Bio-Linux Bio-PC recipes Software HELP files Help Desk

20 Dawn Field dfield@ceh.ac.uk Centre Overview: April 2003 Centre Funded labs GeNet microarray repository EST sequence warehouse GeneSpring microarray analysis software EST pipeline Bio-Linux Bio-PC recipes Software HELP files Help Desk

21 Dawn Field dfield@ceh.ac.uk Centre Overview: Aug 2003 Centre Funded labs GeNet microarray repository EST sequence warehouse GeneSpring microarray analysis software EST pipeline Bio-Linux Bio-PC recipes Software HELP files Help Desk

22 Dawn Field dfield@ceh.ac.uk Centre Overview: Future Centre Funded labs GeNet microarray repository EST sequence warehouse GeneSpring microarray analysis software EST pipeline Bio-Linux Bio-PC recipes Software HELP files Help Desk

23 Dawn Field dfield@ceh.ac.uk Centre Overview: Future Centre Funded labs GeNet microarray repository EST sequence warehouse GeneSpring microarray analysis software EST pipeline Bio-Linux Bio-PC recipes Software HELP files Help Desk

24 Dawn Field dfield@ceh.ac.uk Centre Overview: Future Centre Funded labs GeNet microarray repository EST sequence warehouse GeneSpring microarray analysis software EST pipeline Bio-Linux Bio-PC recipes Software HELP files Help Desk

25 Dawn Field dfield@ceh.ac.ukSummary New Thematic, New Centre Efforts are focused on solutions that take advantage of existing UK Bioinformatics projects, provide scalability, open access, and aim to produce added value data sets expertise, tools, data holdings for environmental genomics researchers Dawn Field, Director of Centre: dfield@ceh.ac.uk Jason Snape, Science Co-ordinator: jason.snape@brixham.astrazeneca.com Fiona C. Knight, Programme Co-ordinator: fclk@nerc.ac.uk http://envgen.nox.ac.uk/

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