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Karlijn van Aerde. Two independent cortical subnetworks control spike timing of layer 5 pyramidal neurons during dynamic β oscillation shifts Karlijn.

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Presentation on theme: "Karlijn van Aerde. Two independent cortical subnetworks control spike timing of layer 5 pyramidal neurons during dynamic β oscillation shifts Karlijn."— Presentation transcript:

1 Karlijn van Aerde

2 Two independent cortical subnetworks control spike timing of layer 5 pyramidal neurons during dynamic β oscillation shifts Karlijn van Aerde et al, VU University Amsterdam Fast network oscillations (beta range) are dynamic! - in rat brain slices - in awake rats - in human EEG What is the underlying network? Or should I say… networks!

3 Adrien Peyrache

4 Time Course of Reactivation in the Prefrontal cortex Adrien Peyrache, K. Benchenane, S Wiener, F Battaglia Arrival Sleep PRE Sleep POST Time (s) Frequency (Hz) Recordings LFP Recordings LFP, Spikes PFC Hippocampus

5 Sleep POST Sleep PRE 1 st PC coefficient delta/spindles events frequency (Hz)‏ reactivation measure Hippocampal filtered LFP (100-300 Hz)‏ cells ensemble activity

6 Iris Grothe

7 Attentional modulation of coherence between monkey area V1 and V4 Iris Grothe Bernstein Group for Computational Neurosciences Bremen Germany

8 160 117 85 62 45 33 24 18 0 24 6 0246 160 117 85 62 45 33 24 18 0.25 0.20 0.15 0.10 0.05 0.25 0 0.0005 0.005 0.05 0.5 0 160 117 85 62 45 33 24 18 0 24 6 Time (s) Frequency (Hz) Coherence P-value Attentional modulation of coherence between monkey area V1 and V4 Iris Grothe Bernstein Group for Computational Neurosciences Bremen Germany

9 Alexander Hanuschkin

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11 Magteld Zeitler

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13 Michiel Remme

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15 Paolo Bonifazi

16 04000200030001000 0 0.2 0.4 0 100 200 Fraction Cell (#) Time (frames) IDENTIFICATION OF CELLULAR NETWORK HUBS DRIVING OSCILLATIONS IN THE DEVELOPING HIPPOCAMPUS 0 50 100 150 200 9709759809859909951000 0 0.2 0.4 Recording and “perturbation” of cells partecipating in build up of network synchrony

17 Fraction of cells 0 0.05 0.1 0.15 0.2 0 pA +40 pA -75 mV -45 mV Cell-network interaction 200 µm oo Morphology PerturbatingNot perturbating Network topology (based on functional connectivity) P. Bonifazi - M. Goldin Y. Ben-Ari R. Cossart INMED, Marseille (France)

18 David Chik

19 Synchronization model of multi-stable perceptions

20 Saskia Haegens

21 Oscillatory brain activity during human somatosensory working memory maintenance  What is the role of primary and secondary sensory regions in working memory?  Which oscillations are involved?  MEG, median nerve stimulation, delayed-match-to-sample task: SII SI Primary somatosensory cortex (SI)

22 Saskia Haegens F.C. Donders Centre for Cognitive Neuroimaging October 14, 2015 Oscillatory brain activity during human somatosensory working memory maintenance alpha ↑ alpha ↓ gamma ↑ Main conclusions:  Sustained gamma band activity reflects working memory maintenance; first in SI and then bilaterally in SII.  Alpha band activity reflects functional inhibition of task-irrelevant regions.


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