1. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Paracelsus Paracelsus was so grandiose And perhaps just a little bit gross Manure, blood, and sand and thus you create man But what makes it a poison is dose! The Undecided Dose Too much of a thing makes you blue But not having it can kill you too Too much or too little Let's not be so fickle We'll go Dutch and divide it by two. Limericks by Toni Hayes

2. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology

3. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology A Small Dose of Toxicology Welcome !! Introduction to the Health Effects of Chemicals Steven G. Gilbert, PhD, DABT www.asmalldoseof.org www.toxipedia.org

4. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Objective Increase our understanding of how chemicals affect human health.

5. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Course evaluation – Very important Other stuff!!! Ask questions – Talk to me!!! Logistics

6. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Special Thank you to: Those that really make this happen Thanks to Organizers

7. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology 9:00Welcome to “A Small Dose of Toxicology” 9:10An Introduction to Principles of Toxicology 10:30Break 10:45Non-Cancer and Neurotoxicology 11:45Q&A Basic toxic 12:00Lunch on your own 1:00Case Study: Health Effects of Lead 2:00An Intro to Reproductive and Developmental Toxicology 2:45Break 3:00Pollution in People - Biomonitoring 3:30Precautionary Assessment – Beyond Risk Assessment 4:15Questions and AnswersAll 4:30Adjourn A Small Dose of Toxicology

8. Welcome to Small Dose of Toxicology A Small Dose of Toxicology See: www.asmalldoseof.org -- smdosesmdose

9. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Small Dose of Toxicology

10. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Milestones of Toxicology

11. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology www.toxipedia.org A free toxicology encyclopedia and resource center that anyone can edit. Toxipedia provides comprehensive, accurate, and scientifically based information on the hazards and risks of chemical and physical agents, with the goal of advancing human and environmental health. Toxipedia – www.toxipedia.org

12. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Healthy World Theater Healthy World Theater reaches to the heart to promote awareness and understanding through the arts to create a more healthy and peaceful world so that all creatures may reach, maintain, and enjoy their potential. Coupling art and science to forge a more healthy and peaceful world www.healthyworldtheater.org

13. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Healthy World Theater Coupling art and science to forge a more healthy and peaceful world HWT Lyceum – Sept. 29 th – Seattle, WA www.healthyworldtheater.org

14. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology NW Public Health See: http://healthlinks.washington.edu/nwcphp/nph/ nwph Public Health and the Precautionary Principle By Steven G. Gilbert

15. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology Child Health

16. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology So Many Chemicals so Little Data 2863 above 1 Million pounds 78.2% no data 21.4% some data 12 or 0.4% good data www.preventingharm.org

17. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology  Nearly 12 million children (17%) under age 18 in the US suffer from one or more developmental disabilities  Learning disabilities – 5-10% of kids in public school  ADHD – 3-6% of all school kids, maybe higher The Consequences

18. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology A Small Dose of – web site A Small Dose of Toxicology www.asmalldoseof.org

19. A Small Dose of ToxicologyWelcome to Small Dose of Toxicology A Small Dose of Toxicology