1. Center for Excellence in Research “Managing a Scientific Laboratory” Navigating the University M. Elizabeth Fini, PhD Director, USC Institute for Genetic Medicine Professor of Cell & Neurobiology and Ophthalmology KECK SCHOOL OF MEDICINE OF USC

2. Session 5: Navigating the University Agenda 3:15 pm – 5 pm 1 hour and 45 minutes Presentations: 10 minutes each (I hour) Core Laboratories – Elizabeth Fini Research Administration – Jeri Muniz Research Ethics & Integrity – Dan Shapiro & Susan Rose Research Advancement – Steve Moldin Technology Transfer – Chris Moulding Postdoctoral Affairs – Mark Todd

3. Research Support Organization at USC University Level (President/Provost) School Level (Deans) Department Level (Academic/Institute) (Chairs/Directors)

4. University, School, Department Services Distributed Model University Level –Animal Resources –Research Administration –Foundation Relations –Postdoctoral Office School Level –Research Administration –Foundation Relations –Postdoctoral Office Department Level –Research Administration

5. Affiliated Hospitals Flatter Structure Hospital Level Animal Resources Research Administration Foundation Relations Department Level Administration intersect with University and the Keck School of Medicine in a number of complex ways

6. University Level President’s Office Office of Administration –Office of Compliance (Dan Shapiro) –Office of Career & Protective Services Environmental Health & Laboratory Safety (Ed Becker) Office of University Advancement –Foundation Relations

7. University Level Provost’s Office Office of Research –Washington, DC Res Advance (Steve Moldin) –Animal Resources (Don Casebolt) –Human Subjects Protection (Susan Rose) –Research Administration (Jeri Muniz) –Stevens Institute for Innovation Office of Technology Transfer (Chris Moulding) Office of the Executive Vice Provost –Postdoctoral Office (Mark Todd)

8. Core Laboratories Elizabeth Fini

9. Research Support Organization at USC University Level (President/Provost) School Level (Deans) Department Level (Academic/Institute) (Chairs/Directors) Research Centers and Core Resources

10. Southern California Clinical & Translational Science Institute Provides Research Expertise, Support for Translation, Human Studies & Clinical Trials, Statistics & Data Management, Training. –Clinical Translation –Research Development –Translational Research Informatics –Community Engagement –Biostatistics and Bioinformatics Resources –Education, Career Development, and Ethics –Preclinical Translation and Regulatory Support International Center for Regulatory Science(Frances Richmond)

11. Research Core Facilities & Resources Two Types: 1. Laboratory Cores –Provide specialized instrumentation and technical services, not possible to support in a single lab –Examples: Imaging Lab, DNA Sequencing Lab, Proteomics Lab 2. Specialized Expertise –Provide disciplinary expertise and services –Examples: Statistical Support, Regulatory Support

12. Research Core Resources at USC Usually located and managed within a Department Each Core Resource is directed by a faculty member with expertise in the technology or discipline School or Department pays start-up costs Ongoing School or Departmental subsidy University often provides for equipment start-up or equipment upgrades Investigator pays fee for service Open equally to all investigators

13. Grant Supported Core Resources Many core resources are supported by “Center” grants or “Core” grants (usually NIH) Each grant supported “Module” is directed by a senior faculty member with expertise in the area Grants pay salary of technical staff, support instrumentation maintenance, provide some centralized supplies – therefore, service fee is reduced May also buy pieces of the core resource on a grant Priorities for use (who is served, and who is served first), and access (what projects are first)

14. Websites Describing University Core Resources Office of Research Facilities Page: http://research.usc.edu/facilities/ http://research.usc.edu/facilities/ Southern California Clinical & Translational Science Institute Research Core Facilities Page: http://sc- ctsi.org/index.php/core- resources/research_core_facilitieshttp://sc- ctsi.org/index.php/core- resources/research_core_facilities Keck School of Medicine Research Facilities & Resources Page: http://keck.usc.edu/Research/Facilities_and_Resources. aspxhttp://keck.usc.edu/Research/Facilities_and_Resources. aspx

15. Thank you!