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Injectable alginate/poly(γ- glutamic acid)/f127 gel for bone formation and differentiation.

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Presentation on theme: "Injectable alginate/poly(γ- glutamic acid)/f127 gel for bone formation and differentiation."— Presentation transcript:

1 Injectable alginate/poly(γ- glutamic acid)/f127 gel for bone formation and differentiation.

2 Cellulose (CELLU) ( rejected ) Textile Research Journal - Manuscript ID TRJ-14-0115 ( rejected ) eXPRESS Polymer Letters (EPL-0005595) ( rejected )

3 Preparation of gel samples Swelling ratios test Water retention capacity test Tensile tests Evaluation of platelet adhesion Blood coagulation test Cell culture and MTT assay

4 Table 1. The preparation and the compositions of hydrogel blends Ingredient Designation Aalginate CaCl 2 A-C Na-PGA(with CaCl 2 )A-NP Ca-PGA 0% F127A-CP 5% F127A-CP-5F 10% F127A-CP-10F 15% F127A-CP-15F 20% F127A-CP-20F 25% F127A-CP-25F 30% F127A-CP-30F

5 Figure 1 The swelling ratio of A-C, A-NP, A-CP, and A-CP-F series hydrogels with normal saline at different pH.

6 Figure 2 The swelling ratio of A-C, A-NP, A-CP, and A- CP-F series hydrogels in DI water at different temperature.

7 Figure 3 The water retention of A-C, A-NP, A-CP, and A- CP-F series hydrogels with the increase of centrifugal force.

8 Figure 4 Tensile strength and breaking elongation of A-CP-F series hydrogel.

9 Figure 5 The dependence of the adsorption amount of HSA and HPF on A-C, A-NP, A-CP, and A-CP-F series hydrogel.

10 Figure 6 The platelet adhesion of A- C, A-NP, A-CP, and A-CP-F series hydrogels.

11 Figure 7 Comparison of anticoagulati on time of A-C, A-NP, A-CP, and A-CP-F series hydrogels.

12 Figure 8 MTT assays of A-C, A- NP, A-CP, and A-CP-F series hydrogels with MG63 cell.


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