1. Doctor Athletes Foot Verruca/wartsCold soresSwine flu Which of these infections would antibiotics work on? – WHY? A B C D

2. Prescribe! Athletes Foot Verruca/wartsCold soresSwine flu EXT Q: Which of these infections would antibiotics work on? – WHY? A B C D NONE of THEM!!

3. Antimicrobials Lesson Learning Outcomes: Increasing Difficulty Describe how antimicrobials work Suggest when it would be appropriate to prescribe antibiotics Explain how bacteria can become resistant to antibiotics

4. Antimicrobials Anti – means ‘against’ Microbial – refers to micro organisms: fungi, bacteria and viruses Anti-microbial chemicals and drugs used for infections DO NOT work on all microbes

5. Antimicrobials… VIRUS FUNGUS BACTERIA Anti- Viral Anti- Fungal Anti- biotic

6. __________________________________ __________________________________ __________________________________ __________________________________ __________________________________ __________________________________ __________________________________ __________________________________ __________________________________ __________________________________ __________________________________ Antimicrobials Summary Describe what an antimicrobial is Right hand page Left hand page

7. The Role of Antibiotics Watch the video THEN write a summary of what you have learnt

8. Antibiotic Resistance Practical Student One Collect an agar plate, permanent pen and ruler On the base (side with the agar jelly in) use the pen to split the plate into four Along the edge of each quarter write the following along with your initials Take the marked plate to one of the two stations with the E-coli bottles and cotton swabs. AT THE STATION: Using a new swab, as shown, dip it into the E-coli bottle ONCE and rub swab over agar jelly from one side to other. Make sure you have covered the whole plate with E-coli. Place swab in Haz-bag after use. Student Two Collect and setup a Bunsen burner with a heat mat Light the Bunsen and leave it on the safety (orange) flame Collect a set of tweezers in ethanol Collect two green paper towels and four hole punched discs from beaker. Place the discs carefully onto one towel. Flame tweezers, as shown, then pick up one disc and spare paper towel and take to one of the four stations of antibiotic solutions. AT THE STATION: Holding the disc in the tweezers dip it into the antibiotic solution ONCE and shake off excess solution onto paper towel. Return to your Bunsen burner your partner should have returned with the agar plate. Place the disc carefully, as shown, into the centre of the correct quarter that matches the dipped solution. Repeat from flaming step for other three quarters and seal plate lid with two pieces of sellotape, as shown. 12.5% 100% 25% 50% DNT MJF

9. Antibiotics MRSA is a superbug – what is a superbug?

10. Summary Time Summarise HOW you carried out the experiment and sketch what you expect the plates to look like when we get them back next lesson!