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Published byLandon Maynard Modified over 10 years ago
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Drug Forms and Routes of Administration
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Before FDA approval Rx company must clearly state in what form or forms the drug will be manufactured Rx company must clearly state what routes of administration are determined safe and effective
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Tablets Drug form which contains dried powdered active drug Contains binders and fillers to provide bulk and proper size Many different types of tablets
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Indented line running across the top Can easily be broken into two pieces with a knife to produce two doses Scored Tablets
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Covered with a special coating that resists stomach acid but dissolves in the alkaline environment in small intestines Enteric Tablets
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Slow-release Tablet Provide a continuous, sustained release of a certain drug Abb as SR slow-release or LA long acting
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Caplets- Tablets Coated tablets in the shape of a capsule Easier to swallow
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Lozenges- Tablets Formed with a harden base of sugar, water and flavorings never swallow dissolve slowly in mouth
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Capsule Comes in two varieties generally easier to swallow
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Soft gelatin- Capsule Manufactured in one piece in which the drug is in a liquid form inside the soft shell
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Hard shell- Capsule Manufactured in two pieces that fit together and hold the drug which is in a powder or granular form
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Creams A semisolid emulsion of oil and water- main ingredient water emulsifying agent added to keep mixed
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Ointment Semisolid emulsion of oil and water- main ingredient oil normally applied to skin without precise measurement nitroglycerin- exception
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Lotion Suspenion of an active drug in a water base
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Powder Finely ground form of an active drug can be contained in a capsule glass vials- sterile water packaged- water
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Liquids Comes in one of 2 forms- Solution or suspension Solution never need to be mixed Solution drug fully dissolved
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Types of Solutions Elixirs-alcohol & water base with added sugar & flavoring Syrups-sugar, water & flavoring thicker Tinctures- alcohol & water base used topically
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Liquid Sprays Water & alcohol base pump or aerosol spray some dispened as foams
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Suspensions Contain fine, undissolved particles of a drug suspended in a liquid base Important to always shake before use
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Suspension Types Water base- distilled or sterile emulsion- fat particles & water gel-suspended in a thicken water medium- does not have to be shaken
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Suppository A solid base of glycerin or cocoa butter containing the drug Rectal or Vaginal Adult or pediatric sizes
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Transdermal Consist of a multi-layered disk of a drug reservoir, a porous membrane and a adhesive layer to it to the skin Patches
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Pellet/Bead Drug can be implanted in the body in the form of a pellet or bead that slowly releases into tissue
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