Presentation on theme: "International Laboratory Capacity Building (Lab Cap)"— Presentation transcript:
1International Laboratory Capacity Building (Lab Cap) American Society for MicrobiologyInternational Laboratory Capacity Building (Lab Cap)Steven Specter, PhD, Chair of the ASM International Laboratory Capacity Building Committee (Lab Cap)
2American Society for Microbiology The oldest & largest life science organization in the worldMembership >42,000 worldwide (30% reside outside the United States)ASM members represent 26 disciplines of microbiological specialization plus a division for microbiology educatorsPublications and journalsTranslated books11 journals covering the spectrum of microbiologyMicrobe – the News Magazine of ASMMeetings and conferenceASM General MeetingInterscience Conference on Antimicrobial Agents & Chemotherapy (ICAAC)
3International Affairs Ensuring that ASM's products & services effectively serve its international membership & the broader international microbiological community;Establishing collaborative relationships with international societies & organizations;Fostering access to microbiological knowledge worldwide;Developing programs that address issues of global concern.
4International Affairs The International Affairs Department is under the following structure:International CommitteeInternational Membership CommitteeInternational Education CommitteeInternational Laboratory Capacity Building (Lab Cap) Committee
5International Laboratory Capacity Building (Lab Cap) Program Capacity Building of Global Clinical Microbiology LaboratoriesCooperative agreement with Centers for Disease Control and Prevention (CDC) – signed in Fall 2005Technical support to the CDC’s Global AIDS Program (GAP) & U.S. Presidents Emergency Plan for AIDS Relief (PEPFAR) initiatives – activities initiated in Fall 2006Technical support to the CDC’s Global Disease Detection Program for five sites of the International Emerging Infections Programs (IEIP) – activities to commence Fall 2007
6American Society for Microbiology – Comparative Advantage ASM’s main strength is its more than 42,000 members, >5,000 of which are clinical microbiologists. ASM is rapidly able to engage numerous experts as volunteers to provide clinical microbiological technical assistance.Other key points:Many ASM clinical microbiologists are nearing retirement and/or have the capacity to travel in their current positions; andMany ASM clinical microbiologists have spent years developing quality assurance/quality control (QA/QC) programs, managing labs, instituting good laboratory practices (GLPs), and training on and designing diagnostic tools/procedures.
7American Society for Microbiology – Comparative Advantage Upon requests for technical assistance, ASM sends out calls to its massive membership to quickly mobilize world renown experts.Examples include:October 2006 request for TB diagnostic experts – database of 200 qualified individuals compiled in 1 monthAugust 2007 request for TB lab infrastructure design and renovation experts – current database includes 52 qualified individuals, compiled in 2 weeks
8PEPFAR-funded Countries Currently Requesting Technical Assistance (TA) from ASM Botswana – OIs/TBCote d’Ivoire - TBKenya - OIsMozambique – OIsNamibia – TBNigeria – TB/OIsZambia – TB/OIsZimbabwe - SOPs
9OI/TB Diagnostic Capacity Building BotswanaASM to provide technical support for strengthening clinical laboratory diagnostics for common OIs, as well as to the National Tuberculosis Reference Laboratory (NTRL) for TB diagnostics.
10TB Diagnostic Capacity Building Côte d’IvoireASM to provide technical assistance to the national TB laboratory network for infrastructure design and renovation of labs to support TB culture and drug susceptibility testing (DST); support for training in Lowenstein-Jensen and liquid (MGIT 960) culture, DST, and identification.
11OI/TB Diagnostic Capacity Building KenyaASM is working with CDC-Kenya and the Kenyan National Public Health Laboratories (NPHL) to establish a central microbiology laboratory at the NPHL to serve as a reference microbiology laboratory. This will strengthen the organizational structure of the NPHL to establish and offer clinical microbiology services to HIV/AIDS patients countrywide.Kenya is also interested in expanding their TB culture capacity with the BD MGIT 960 at multiple sites, which ASM may help support.
12OI Diagnostic Capacity Building MozambiqueASM to provide technical assistance to its laboratory system, specifically for the strengthening of diagnostics for common OIs through laboratory infrastructure improvement and training of laboratory personnel.
13TB Diagnostic Capacity Building NamibiaSince Fall 2006, ASM is assisting the Namibia Institute of Pathology (NIP) to:Renovate central TB lab for efficient and quality testing and establishing a safe work environmentStrengthen TB lab staff at central and peripheral labsImprove quality of testing for TB smear microscopy, culture, & drug susceptibility testing (DST)
14OI/TB Diagnostic Capacity Building NigeriaASM to develop a comprehensive QA/QC system for TB; suggest improvements to the AFB Microscopy training curriculum currently used in Nigeria; provide technical expertise on the structural design of new and existing labs for TB culture/DST; and improve training for simple OI diagnostics (emphasis on microscopy).
15OI/TB Diagnostic Capacity Building ZambiaSince Fall 2006, ASM has offered support with strengthening basic bacteriology and the implementation of new technologies for AFB microscopy, blood culture, TB culture, and DST.
16SOP Writing Capacity Building ZimbabweDuring a 2-week TA mission, ASM assisted CDC-Zimbabwe & ZINQAP to:Review the National Clinical SOPs for accuracy & contentDevelop & include procedural details required by the International Organization for Standardization (ISO) that were not in the original SOPsTranscribe SOPs into the ISO formatDevelop QC procedures that would meet minimum ISO standards.
17ASM Lab Cap Successes Large pool of technical experts to select from ASM membership >42,000Providing timely advice on laboratory renovations, equipment and supply needsDetailed lists on lab renovation requirements, equipment and supply needs have enabled countries to better allocate their fundsMentoring that has enabled visible, immediate results in improving laboratory diagnosis of TB and OIsMaintenance of relationships with in-country laboratoriansASM consultants’ expertise has lead to constant requests from in-country laboratorians to have them return and ongoing, even remote relationships have been maintained
18ASM Lab Cap SuccessesCollaborations with key individuals from international agencies such as CDC, WHO, International TB Union, Merieux Foundation, FIND, leading to development of experience-based best practicesPulling from strong international collaborators to gain information on activities already ongoing in-country and harmonizing our efforts accordinglyDeveloping and harmonizing international training tools for TB and OIsDeveloping specific national strategic plans and scopes of work for each consultantShorter term contracts leading to more frequent monitoring and evaluation of deliverables
19ASM Lab Cap ChallengesLimited comprehension of TB/OIs and the long-term commitment needed to build capacityUnderestimation of the amount of TA needed to implement TB and OI proceduresLimited resources (i.e. training materials, SOPs, etc) available for OI diagnosis in low-income settingsMisunderstanding of technical consultancy vs. implementing partner rolesInconsistencies in ability to communicate with in-country USG contactsLapses in three-way communication between CDC-ATL, CDC-country staff, and CoAg partner
20Most Successful Operating Environments Supportive Ministry of Health and National ProgramsGood working relationships between National Reference Lab and corresponding National ProgramsCollaboration between National AIDS Program and Microbiology-related Programs (i.e. NTP)TB Expert and/or Microbiologist within USG teamFacilitates proper planning; creates continuity in activities; enables knowledge sharing