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COUNTERCURRENT MULTIPLICATION countercurrent multiplication refers to the ability of the kidney to increase the osmolality of the interstitium from the.

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Presentation on theme: "COUNTERCURRENT MULTIPLICATION countercurrent multiplication refers to the ability of the kidney to increase the osmolality of the interstitium from the."— Presentation transcript:

1 COUNTERCURRENT MULTIPLICATION countercurrent multiplication refers to the ability of the kidney to increase the osmolality of the interstitium from the normal tissue value of 300 mosm/kg up to 1200-1400 mosm/kg this is necessary to allow the kidney to be able to concentrate the urine

2 COUNTERCURRENT MULTIPLICATION 300 TIME 0

3 COUNTERCURRENT MULTIPLICATION 300 500100 300 TIME 1 NaCl 200 mosm

4 COUNTERCURRENT MULTIPLICATION 300 500 300 500300 100 300 TIME 2 NaCl 200 mosm NaCl 200 mosm

5 COUNTERCURRENT MULTIPLICATION 300 500 700500 300 100 TIME 3 NaCl 200 mosm NaCl 200 mosm

6 COUNTERCURRENT MULTIPLICATION 300 700 500 700500 300 100 TIME 4 NaCl 200 mosm NaCl 200 mosm NaCl 200 mosm

7 COUNTERCURRENT MULTIPLICATION 500 900 700 900700 500 300 TIME 5

8 COUNTERCURRENT MULTIPLICATION 700 1100 900 1100900 700 500 TIME 6

9 COUNTERCURRENT MULTIPLICATION 700 1100 900 1100900 700 500 TIME 7

10 COUNTERCURRENT MULTIPLICATION 300 500 300 100 300 500 100 300 500 700 500 700 900 700 900 1100 900

11 COUNTERCURRENT MULTIPLICATION THE ROLE OF UREA Loop CD Water urea

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