Presentation on theme: "Outcome of Surgical Sperm Retrieval (SSR) followed by ICSI in men with obstructive azoospermia University of Aberdeen Assisted reproductive unit D.Giannaris,"— Presentation transcript:
Outcome of Surgical Sperm Retrieval (SSR) followed by ICSI in men with obstructive azoospermia University of Aberdeen Assisted reproductive unit D.Giannaris, S.Bhattacharya, M.Hamilton
Obstructive azoospermia Typical features Vasectomy and failed reversal surgery CAVD Other cases - Normal karyotype - Normal FSH (<14) - Normal testicular biopsy - Testicular size
STUDY GROUPS Group A: Failed reversal vasectomy (n=83) Group B: CAVD (n=16) Group C: Obstruction of other causes (n=33) 12 patients with non-obstructive azoospermia
4 S.S.R results Total No n Sperm Retrieved n % Group A n=83 100% Group B n=16 n=15 94% Group C n=33 n=29 88%
Live births & ongoing pregnancies % per cycle started (NS)
Patient & treatment profiles (Pregnant vs Non-pregnant) No differences in: embryos grade embryos stage male age female age 1y vs 2y female infertility male smoking female smoking Statistical significant difference in: female pathology
Conclusions S.S.R is effective in obstructive azoospermia. Failed vasectomy reversal group have the best prognosis. Cases other than vasectomy reversal or CAVD were associated with fewer motile sperm, lower implantation rate and lower live birth rate. Few numbers to demonstrate statistical significance.