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Biotechnology Development: Opportunities and Challenges Dr Prakash Ghimire, Ph D Associate Professor Microbiology Tribhuvan University Microbiologist,

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Presentation on theme: "Biotechnology Development: Opportunities and Challenges Dr Prakash Ghimire, Ph D Associate Professor Microbiology Tribhuvan University Microbiologist,"— Presentation transcript:

1 Biotechnology Development: Opportunities and Challenges Dr Prakash Ghimire, Ph D Associate Professor Microbiology Tribhuvan University Microbiologist, WHO-IPD/NPHL/EDCD-MoH

2 Ecological Zones and Development Regions of Nepal Mountains (16 districts) Hills (39 districts) Terai (20 districts) Far-Western Region Mid-Western Region Western Region Central Region Eastern Region

3 Biotechnology: Animal Animal –Hybrids Pharmaceutical Pharmaceutical –Diagnostic –Therapeutic –Vaccines Plant Plant –Agriculture - NARC –Food

4 Biotechnology: Post Human genome situation Post Human genome situation –Proteomics & Genomics – two closely related area Cell biology Cell biology Immunology Immunology –Antibodies Polyclonal Polyclonal Monoclonal Monoclonal Molecular biology Molecular biology –Genomics –Proteomics

5 RONAST

6 RONAST ACTIVITIES: RESEARCH ACTIVITIES ACTIVITIES: RESEARCH ACTIVITIES Biotechnology Programs - Biotechnology Programs - –Conservation of Medicinal and Aromatic Plants [Click Here]- Molecular Diagnostic of Citrus greening Disease – Conservation of Medicinal and Aromatic Plants [Click Here]Conservation of Medicinal and Aromatic Plants [Click Here] –Molecular Characterization of Medicinal plants -Tea clones -Bacillus thuringinsis – Molecular Characterization of Molecular Characterization of –Flora of Nepal Project Research on Organic Farming -Antagonistic Study of Ectomycorrhiza -Study of the role of Endomycorrhiza Flora of Nepal Project Research on Organic Farming Flora of Nepal Project Research on Organic Farming Natural Products Research -Bioprospecting of Cordyceps sinensis- Biopesticides study program -Analytical services Natural Products Research -Bioprospecting of Cordyceps sinensis- Biopesticides study program -Analytical services Natural Products Research Natural Products Research

7 Nepal Health Research Council Supports health Research Supports health Research –Mostly in health system research –Negligible investment in Biotechnology

8 Medical Biotechnology In Nepal Immunology: Immunology: –Vaccine Production Rabies Vaccine Production (Central Veterinary Research Laboratory), Tripureswor Rabies Vaccine Production (Central Veterinary Research Laboratory), Tripureswor –Antibody Production Everest Biotech Everest Biotech –Founded by biochemists at Oxford University, based in Oxfordshire, UK with a production laboratory established in Kathmandu. –CDM TU- Non commercial/Academic Use Antibody Production, Purification…….. Antibody Production, Purification…….. –National Public Health Laboratory Health Services Health Services –Flow cytometric assay ( FACS)

9 Medical Biotechnology Molecular Biology Molecular Biology –DNA Sequencing – Proposed at National Forensic Laboratory, Khumaltar –PCR RONAST- Plant molecular biology RONAST- Plant molecular biology CDMTU – Tropical diseases- Malaria, Leishmania etc. CDMTU – Tropical diseases- Malaria, Leishmania etc. National Public Health Laboratory, Teku- SARS, Malaria, etc. National Public Health Laboratory, Teku- SARS, Malaria, etc. VBDRTC, Hetauda- Malaria, Leishmania VBDRTC, Hetauda- Malaria, Leishmania Mycobacterial research Laboratory, Lele- Tuberculosis, Leprosy Mycobacterial research Laboratory, Lele- Tuberculosis, Leprosy Universal College/ RLAAB- Plant mol. Bio. Universal College/ RLAAB- Plant mol. Bio. Veterinary Research Laboratory, Tripureswor- Veterinary Research Laboratory, Tripureswor- Si-Gan Health Foundation, Maharajgunj Si-Gan Health Foundation, Maharajgunj –Real Time PCR ( Proposed) National Public Health Laboratory, Teku National Public Health Laboratory, Teku –Avian Influenza diagnostic service Cell Biology Cell Biology

10 Real-Time PCR

11 Challenges: Machines without consumables Machines without consumables –Academic & HMG Institutes Training of Human Resources Training of Human Resources –Latest updates Research Culture Research Culture –Carrer prospects Research Funding & Collaboration Research Funding & Collaboration –NHRC ? –Big researches- Survey type, No Laboratory capacity development in Nepal Availability of Consumables in local market Availability of Consumables in local market –Mostly not available, If available, costs 3-5 times of original cost Entrepreneurship Entrepreneurship –Market

12 Hope for Future New University programs as per market requirements New University programs as per market requirements –Medical technology Program –Medical Microbiology Program –Pharmaceutical Sciences Program –Biotechnology Program –Allied health Programs ( Radiology, Dentistry, Physiotherapy, Bio-medical Engineering, …….) Availability of funding in post WTO scenario Availability of funding in post WTO scenario Introduction of newer Pharmaceutical companies Introduction of newer Pharmaceutical companies Availability of trained /cost effective HRs Availability of trained /cost effective HRs Worldwide market in post WTO situation Worldwide market in post WTO situation Coming up of new diagnostic companies Coming up of new diagnostic companies Positive Government Policy ? Positive Government Policy ?

13 Formula for Success A small truth to make our life 100% successful…… A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

14 None of them makes 100% LUCK % LOVE % EFFORT % KNOWLEDGE % HARDWORK %

15 Then what makes 100% Is it money? …No!!! Is it money? …No!!! Is it leadership? …No!!! Is it leadership? …No!!! Every problems has a solution, so perhaps Every problems has a solution, so perhaps Change our ATTITUDE It is ATTITUDE towards life and work that makes Our Life 100% Successful

16 Dont you think so ?!?!?!?! ATTITUDE %

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