Presentation on theme: "Muscular System by: Daniel Gable"— Presentation transcript:
1Muscular System by: Daniel Gable An overview of the muscular system
2Muscles move skeletal parts by contracting Muscles always contractMuscles must be attached in antagonistic pairs so each muscle can work against each otherSkeletal muscle is attached to the bones and is responsible for their movement, it is characterized by a hierarchy of smaller and smaller parallel unitsA skeletal muscle consists of a bundle of long fibers running the length of the muscle
3Each fiber is a single cell with many nuclei, reflecting its formation by the fusion of many embryonic cells. Each fiber itself a bundle of smaller myofibrils arranged longitudinally. The myofibrils in turn are composed of two kinds of myofilaments. Thin filaments consist of two strands of actin and one strand of regulatory protein coiled around one another, while thick filaments are staggered arrays of myosin molecules. Each repeating unit is a sarcomere, the basic contractile unit of the muscle.
4Interactions between myosin and actin generate force during muscle contractions When a muscle contracts the length of each sacomere is reducedThis is known as the sliding-filament model where neither the thin or thick filaments change length but rather slide past each other longitudinallyThe myosin head is the center of bioenergetic reactions that power muscle contractionsMuscle cells typically only store enough ATP for a few contractions
5Calcium ions and regulatory proteins control muscle contraction A skeletal muscle contracts only when stimulated by a motor neuronWhen at rest the myosin binding sites on the actin molecules are blocked by the regulatory protein tropomyosinThe troponin complex controls the position of tropomyosin on the thin filamentWhen calcium concentration in the cytosol falls, the binding sites of actin are covered, and contraction stopsCalcium concentration in the cytosol of the muscle cell is regulated by the sarcoplasmic reticulum, a specialized endoplasmic reticulumThe action potential spreads deep into the interior of the muscle cell along infoldings of the plasma membrane called T (transverse) tubules
6Diverse body movements require variation in muscle activity Muscles act in twitches and if the rate of stimulation is fast is enough, the twitches will blur into one smooth and sustained contraction called tetanusA motor unit consists of a single motor neuron and all the muscle fibers it controlsTension in a muscle can be progressively increased by activating more and more of the motor neurons controlling the muscle, a process called recruitment of motor neurons
7Fast and Slow Muscle Fibers Fast muscle fibers are used for short, rapid, powerful contractionsSlow muscle fibers, often found in muscles that maintain posture, can sustain long contractionsMygoglobin binds oxygen more tightly than hemoglobin so it can effectively extract oxygen from the blood
8Other Types of MuscleVertebrate cardiac muscle is found in only one place-the heartThe junctions between cardiac muscles contain specialized regions called intercalated discs, where gap junctions provide direct electrical coupling among cellsSmooth muscle lacks the striations of skeletal and cardiac muscle because the actin and myosin filaments are not all regularly arrayed along the length of the cell.