1. Lysyl Project On the influence of lysyloxidase on bone formation Zentrum für Muskel- und Knochenforschung

2. Control mice vs mutant mice control mouse 1 mutant mouse 2 mutant mouse 3 mutant mouse 1 control mouse 2 control mouse 3

3. Control mice vs mutant mice control mouse 1 mutant mouse 2 mutant mouse 3 mutant mouse 1 control mouse 2 control mouse 3

4. Control mice vs mutant mice control mouse 1 mutant mouse 2mutant mouse 3 mutant mouse 1 control mouse 2control mouse 3

5. Segmentation

6. Surfaces Control mouse 3

7. Volume calculation Control mouse 3

8. Volumens and dimensions Volume(mm3)D1 (mm)D2 (mm)D3 (mm) Control mouse1354.5823.643.923.12 Mutant mouse 1386.3622.733.683.11 Control mouse 2367.3022.893.633.19 Mutant mouse 2356.8223.403.552.49 Control mouse 3371.0122.563.603.37 Mutant mouse 3372.8423.163.603.05

9. Lateral view

10. Frontal view

11. Possibilities 1 Finite element analysis

12. Possibilities 2 Increase of resolution