1. AccrualNet™: A Unique Resource for Clinical Trial Professionals NCI Office of Cancer Centers Learning Series March 21, 2013

2. Speakers Linda Parreco, RN, MS Public Health Advisor Office of Partnerships and Dissemination Initiatives NCI, Office of Communications and Education Ellen Richmond, RN, MS Nurse Consultant and Program Director GI and Other Cancers Research Group NCI, Division of Cancer Prevention Annette Galassi, RN, MA, OCN Public Health Advisor Office of Partnerships and Dissemination Initiatives NCI, Office of Communications and Education

3. Objectives Describe how clinical trial accrual affects you Find one opportunity to implement AccrualNet into your practice Explain how AccrualNet’s Community of Practice supports your work

4. Our Common Goal Move science and medicine forward Improve public health Complete trials in a timely fashion

5. Accrual to Clinical Trials Magnitude and impact of insufficient accrual Persistent, but well-documented challenges There are solutions –Growing body of evidence –Focused attention –Everyone plays a role

6. Durivage, Bridges. J Clin Oncol 27: 15s, 2009 Cancer Center Director –Need to demonstrate a successful scientific program BUT….. 14 cancer centers; 2005-2007 54.2% of 2685 studies did not accrue ANY patients Accrual is Everyone’s Challenge

7. Durivage, Bridges. J Clin Oncol 27: 15s, 2009 Kitterman, Cheng, Dilts, Orwoll. Acad Med. 86(11), 2011 Cancer Center Administrator Need to demonstrate effective use of scarce resources BUT….. –3773 hours/year devoted to studies that accrue no patients –$1M: FY2009 economic impact of low- enrolling studies Accrual is Everyone’s Challenge

8. Penberthy, Dahman, Petkov, DeShazo. J Oncol Pract 8:6, 2012 Principle Investigator –Produce an approved protocol that works in the real world of clinics and patients CTO Manager –Incomplete studies squander screening costs – How do you ensure recruitment knowledge/skill, acknowledge success, support career development? Accrual is Everyone’s Challenge

9. Study Coordinator/Research Nurse/CRA –Recruitment strategies Evidence-based vs Tradition –What about new strategies like social media? –Opportunities to attend conferences, training are decreasing –Working in silos

10. Accrualnet.cancer.gov

11. What is AccrualNet? A “one-stop shop” to help clinical trial professionals: Discover effective accrual strategies Locate useful tools and sample materials Find staff and patient education resources Connect with colleagues

12. https://accrualnet.cancer.gov

13. The Protocol Accrual Lifecycle

15. LITERATURE & TOOLS

16. Literature & Tools

17. 1.Consider national and local stakeholder enthusiasm for the trial 2.Evaluate the trial for recruitment feasibility 3.Choose study sites carefully 4.Prepare trial-specific materials Development Stage Strategies/ Checklist/Best Practices

18. Most relevant information Link to the abstract / PDF Title and citation Share with colleagues AccrualNet Resource Pages

19. Highlights Why this item might be useful Details Find Most Relevant Information

20. Find Useful Tools

21. Get The Facts On Insurance Issues

22. Related Practical Tools

23. You can comment on the content “I thought this was a great article. We tried one of the ideas and here’s how it worked…” Comments Please

24. Easily searchable Promising practices –Basic principles and checklists –Uniquely abstracted –Links to the evidence Published papers Tools of the trade –Screening logs –Flyer templates –Media guides Implementing AccrualNet: Literature & Tools

25. 5 minutes: find info YOU can use!

26. EDUCATION & TRAINING

27. Education and Training We heard that you: –Experience significant staff turnover –Spend a lot of time on training –Feel like you may be re-inventing the wheel –Need readily available, credible information and tools

28. Protocol Accrual Lifecycle

29. Education & Training

30. Staff Education

31. Sample Resource Page

32. Patient Education

33. Implementing AccrualNet: EDUCATION Orientation for new staff New researchers Professional development Facilitate use of evidence-based interventions related to accrual Patient education

34. Announcing…Journal Club Quarterly webinar Tor review findings of recently published articles and discuss application to practice Brief presentation followed by discussion Target launch end of April E-mail invite to AN members

35. Already have great tools? SHARE them with the AccrualNet community! Contribute your materials

36. COMMUNITIES & CONVERSATIONS

37. The AccrualNet Community

38. Virtual Community of Practice

39. Benefits for You Overcomes geographic barriers No financial investment Reduces staff isolation Engagement stimulates enthusiasm, focus on overcoming the hurdles Human motivators: recognition and acknowledgment!

40. Who’s in our Community Location –30% academic – 48% community Roles –31% managers – 66% CRA, SC, RN Experience –41% >10 years –25% < 5 yrs 386 members

41. Your Top 5 Areas of Interest Recruitment Community outreach Communication strategies Training and education Site management

42. Ask a question Share your experience Quickly find topics of interest What’s Happening in the Community? Conversations

43. What’s Happening in the Community? Monthly Guest Expert

44. Join or start a Community Protocol Population Sub-specialty Career phase Organization Start Your Own Community on AccrualNet!

45. Now What? AccrualNet puts valuable information at your fingertips AccrualNet helps you train staff AccrualNet is a Community of Practice You’ve Learned 3 Things

46. Lead the Way SAY the message “AccrualNet is a valuable resource” GIVE an example “This article must have been written for us!” MAKE the expectation “We will use it to plan accrual” CLAIM success “Here’s what we did—and it worked!”

47. AccrualNet ToolKit One page flyer to post in clinic Drop-in article for your newsletter Presentation slides with speaker notes Social media posts for your Facebook page

48. UTSA Oregon Health Sciences Fred Hutch Mayo Case Western Put the ‘Share Button’ on your site!

49. We’re here to help you Linda Parreco Ellen Richmond Annette Galassi Cathy Muha Sona Thakkar Harry Kwon Cassie Norman Katherine Jenkins Madeline LaPorta

50. https://accrualnet.cancer.gov