1. HTOP summary Nov-2013 Healthcare Technology Open Platform LLP （ HTOP ） Established ： May, 2011 President: Hiroyuki YOKOI (President of ICST) Managing Director: Fumiaki HIRATA(President of RIKEN Cell Tech) Director: Hiroyuki TOMORI Auditor: Kiyoharu IWATA Mission: To initiate and manage the project as solution against current and future healthcare problems with open network Functions: (1)to organize open brainstorming and feasibility study discussion with various stakeholders.(2) project initiation with proper role allocation Contact: TEL 81-3-6324-2770 E-mail : hirata@htop.or.jp URL ： http://htop.jimdo.com/ http://htop.jimdo.com/ Related URL: http://www.icst.jp/english/http://www.icst.jp/english/ http://rc-t.jimdo.com/ 1

2. Feasibility Study Healthcare Technology Open Platform LLP （ HTOP ） development production Sales and marketing Mock-upprototypetest premarketing Market survey Test sales test HTOP initiates, coordinates and manages project With open network 2 Preparation of mass production http://htop.jimdo.com/

3. Medical device project with HTOP HTOP initiates, coordinates and manages project With open network. HTOP network member -Medical device maker -University hospital -Private Hospital -Clinic -EMR bender -Nursing home -Local Distributer -Sales Representative -Related application maker -Cloud services -Patent attorney -lawyer Foreign products (hardware) Foreign products (software) Japanese market Asian Market (Singapore, Thai, India, china) 3

4. Penetration into medical device market (e.g. patient monitoring devices) HTOP network -Medical device maker -University hospital -Private Hospital -EMR vender -Related application maker -Cloud services Foreign products (hardware) Foreign products (software) University hospital -Evaluation -PMDA Approval -luminary site selection -pre-marketing -total service packaging - Coordination with current system Private hospital EMR vendor 4

5. Client company Business structure: Japanese and Asian medical market Foreign products (hardware) Foreign products (software) HTOP (1)NDA contact with client company (2)Project preparation within HTOP member (3)Decide proper role allocation as project member with HTOP members and its partner (4)Recommend the whole project member ready for turn-key start Partner company, hospital Local distributer, application service, etc HTOP Network member ICST: Marketing approval holder(MAH) RIKEN Cell Tech: Sales rep, project management 5