1. 1 Platelet and global haemostatic effects of common traditional Chinese herbal medicines: implications for anaesthesia KFJ Ng May 2011

2. 2 7 22 (2000) 13 (2003) 7 (2007) 14 (2004) 8 (2006) 13 (2005) 5

3. 3 Ann Pharmacother 2004;38:1651

4. 4 The “Big 3”  Ginkgo biloba (7/29)  Garlic (3/29)  Saw palmetto (2/29)

5. 5 Ginkgo biloba Am J Hematol 2005; 79: 343

6. 6 Ginkgo biloba (EGb 761) Thromb Res 2003; 108: 151

7. 7 Garlic A&A 2007; 105: 1214

8. 8 Garlic Prostaglandins Leukot Essent Fatty Acids 1998;58:257

9. 9 Saw palmetto

10. 10 The “Big 3” and more… Plast Reconstr Surg 2007; 120:2044

11. 11 Fufang (compound formula)

12. 12 Danshen ( 丹參, salvia root)

13. 13 Danshen ( 丹參, salvia root) Platelets 2008;19:24

14. 14 Danshen ( 丹參, salvia root) Thromb Res 2008;123:298

15. 15 Ligusticum wallichii (chuanxiong, Szechuan lovage, “ 川芎 ”)

16. 16 Ligusticum wallichii (chuanxiong, Szechuan lovage, “ 川芎 ”) Thromb Res 2001;104:15

17. 17 Curcuma zedoaria (zedoary, ezhu, “ 莪 朮 ”)

18. 18 Curcuma zedoaria (zedoary, ezhu, “ 莪 朮 ”) Thromb Res 2011;127:111

19. 19 Curcuma zedoaria (zedoary, ezhu, “ 莪 朮 ”) Thromb Res 2011;127:111

20. 20 Angelica Sinensis (dongguai, “ 當歸 ”)

21. 21 Dang-Gui-Shao-Yao-San ( 當歸芍藥散 ) (dong guai, chuanxiong, and others) Am J Chin Med 2005;33:747

22. 22 Radix et Rhizoma Notoginseng (sanqi, “ 三七 ”)

23. 23 Radix et Rhizoma Notoginseng(sanqi, “ 三七 ”) J Clin Pharmacol 2000;40:1150

24. 24 Radix et Rhizoma Notoginseng (sanqi, “ 三七 ”) Pharmacotherapy 2001;21:773

25. 25 Radix et Rhizoma Notoginseng(sanqi, “ 三七 ”) J Ethnopharmacol 2009;125:380

26. 26 Radix et Rhizoma Notoginseng(sanqi, “ 三七 ”) J Ethnopharmacol 2009;125:380

27. 27 Radix et Rhizoma Notoginseng(sanqi, “ 三七 ”) J Ethnopharmacol 2009;125:380

28. 28  Get to know the “ bad guys ”  Know the common ones used in your locality  Back to the basics  Haemostasis testing

29. 29 Can you tell me…  Indication for treatment?  Drug interactions?  Precautions e.g. menstruation?  Bleeding symptoms

30. 30 Test cartridge Cassette Carousel Printer LCD screen Soft keys Trigger solution

31. 31

32. 32 EPICT = 188 sec Sensitivity = 88% Specificity = 52%

33. 33

34. 34 Thank You