1. Nervous System and Senses

2. Neural Activity

3. The Neuron Which direction does a signal travel down a neuron? What do you think a “signal” is? How do you think the neuron controls where the signal goes next?

4. Electrical Events An action potential is an “all or nothing” event. A neuron either sends a signal or it doesn’t. Relative strength or weakness of a signal come from frequency, not size of the potential.

5. Resting potential Using active transport, the neuron moves N+ ions to the outside of the cell and K+ ions to the inside of the cell. Large molecules in the cell maintain a negative charge.

6. Action potential On receiving a stimulus, sodium gates and potassium channels open briefly, allowing these ions to diffuse. The gates close, and active transport restores the resting potential.

7. Traveling Potentials

9. Synapse A gap called a synapse controls the transmission of signals. Neurotransmitters cross the synapse and stimulate the next neuron.

10. Some Neurotransmitters NeurotransmitterLocationSome Functions AcetylcholineNeuron-to-muscle synapseActivates muscles DopamineMid-brainControl of movement EpinephrineSympathetic systemStress response SerotoninMidbrain, pons, medullaMood, sleep EndorphinsBrain, spineMood, pain reduction Nitric oxideBrainMemory storage

11. During resting potential, which channels are closed? 1.Potassium 2.Sodium 3.All 4.None

12. What determines the intensity of a neural signal? 1.Speed of action potential. 2.Size of action potential. 3.Duration of action potential. 4.Frequency of action potentials.

13. During a resting potential, where are most positively-charged particles found? 1.Outside the neuron. 2.Inside the neuron. 3.Equal amounts are found on both sides of the membrane.

14. Sketch a neuron and label the four major parts. Diagram a synapse and show how action potentials travel from one neuron to the next. WORKTOGETHERWORKTOGETHER

15. Information Processing

16. Why a CNS? Neurons control movement. The brain (or spine) interprets sensory signals and determines the appropriate movements (that is, behavior). Appropriate movement is critical to the survival of most animal species. Selection has favored a central nervous system to control responses.

17. Four basic operations Determine type of stimulus Signal the intensity of a stimulus Integrate responses from many sources Initiate and direct operations

18. Type of stimulus How does the brain “know” if a sensory signal is visual, auditory, etc.? Areas of the brain dedicated to specific sensory signals are connected to nerves that connect to specific sensory organs. “Cross-sensory” effects: a poke in the eye produces stimulates the optic nerve, producing visual effects.

19. Intensity of stimulus Intensity = frequency of action potentials

20. Integration of stimuli Convergence = Signals may arrive through many neurons, but may all pass their signal to a single connecting neuron. Such cells may be “decision-making” association neurons that may determine an appropriate output.

21. Directing operations Neural pathways consist of: Sensory neurons Association neurons, which receive signals from many sources Motor neurons Effectors: muscles, glands

22. Reflexes The simplest neural pathway is the reflex arc. This involves one or more sensory neurons, association neurons in the spine, and motor neurons, which carry out the reflex entirely before the brain is aware of the response.

23. Reflex Arc

24. What is the effector in the familiar knee jerk reflex? 1.The knee hammer 2.Sensory receptors in the patellar tendon 3.Sensory neurons running up the leg 4.Motor neurons running down the leg 5.The quadriceps muscles

25. You’re probably all familiar with the knee- jerk reflex, which your doctor uses to test your reflexes. Sketch a reflex arc for the knee jerk reflex, beginning with whacking your knee with a hammer. Label the sensor and effector in your diagram. WORKTOGETHERWORKTOGETHER

26. Organization

27. Neural organization

28. Central Nervous System Consists of brain and spine Functions: Receives sensory signals and determines appropriate response Stores memory Carries out thought

29. Spine: structure The spinal cord is protected by the vertebrae. Gray matter contains cell bodies; white matter contains myelinated fibers. PNS nerves extend outside of the vertebrae.

30. Brain: Structure Hindbrain carries out the most basic functions. Midbrain coordinates signals. Forebrain processes signals, stores memories, creates thought.

31. Peripheral nervous system Nerves, neurons, and sensory organs outside the central nervous system Functions: Sends signals to the CNS Receives and transmits motor signals from the CNS Stimulates effectors

32. Somatic nervous system Motor neurons that control voluntary movements by activating skeletal muscles. Also involved in what we perceive as involuntary movements, such as reflexes (though voluntary control of the muscles involved, such as tensing them, can reduce the response).

33. Autonomic Nervous System Motor neurons that control involuntary responses involving the organs, glands, and smooth muscles.

34. Sympathetic division Portion of the autonomic nervous system that produces the “fight or flight” response: Dilation of pupils Increased heart and breathing rates Constriction of blood vessels Inhibits digestion

35. Parasympathetic Division Portion of the autonomic nervous system that produces the “rest and ruminate” response: Constricts pupils Dilates blood vessels Reduces heart and breathing rates. Stimulates digestion.

36. The central nervous system includes: 1.Brain only 2.Brain and spine 3.Brain, spine, and major nerves 4.Spine and major nerves

37. Motor neurons carry signals which direction? 1.Sensory organs -> CNS 2.Muscles -> CNS 3.CNS -> sensory organs 4.CNS -> muscles

38. Which activity is most likely to activate the sympathetic division of your nervous system? 1.Cuddling kittens 2.Watching an exciting action movie. 3.Meditating 4.Lying in the sun