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Chapter 16 (Part 4) Synthesis of Eicosanoids, Glycerolipids and Isoprenoids.

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Presentation on theme: "Chapter 16 (Part 4) Synthesis of Eicosanoids, Glycerolipids and Isoprenoids."— Presentation transcript:

1 Chapter 16 (Part 4) Synthesis of Eicosanoids, Glycerolipids and Isoprenoids

2 Eicosanoids

3 Eicosanoid Synthesis cyclooxygenase

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6 Glycerolipid Biosynthesis

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10 Mevalonate kinase Phosphomevalonate kinase pyrohosphomevalonate decarboxylase Formation of the isopentenyl pyrophosphate (IPP)

11 Two Fates of HMG-CoA

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13 Condensation of IPP into Polyprenyl Compounds Dimethylallyl pryophosphate IPP isomerase

14 IPP Isomerase prenyltransferase Squalene synthase Cholesterol Synthesis from IPP

15 Squalene monooxygenase 2,3-oxidosqualene lanosterol cyclase cholesterol 20 steps

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